Etiology of breast and gynecological cancers : proceedings of the Ninth International Conference on Carcinogenesis and Risk Assessment, held in Austin, Texas, November 29-December 2, 1995

著者

書誌事項

Etiology of breast and gynecological cancers : proceedings of the Ninth International Conference on Carcinogenesis and Risk Assessment, held in Austin, Texas, November 29-December 2, 1995

editors, C. Marcelo Aldaz ... [et al.]

（Progress in clinical and biological research, 396）

Wiley-Liss, 1997

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Despite recent advances in research and prevention, the incidence of common female cancers is still increasing. This book reviews the most recent advances in the fields of breast and gynecological carcinogenesis. It discusses the validity of animal models for study of these human diseases and addresses the relative contributions of genetic predisposition and environmental exposure to potential carcinogens including environmental hormone disrupters.

目次

  • Toward a unified concept of mammary carcinogenesis
  • epidemiologic analysis of breast and gynaecologic cancers
  • recent advances in the molecular genetics of hereditary breast and ovarian cancer
  • defining etiologic heterogeneity in breast cancer using genetic biomarkers
  • the genetics of sporadic breast cancer
  • molecular epidemiology of breast cancer
  • molecular perspectives on cancer, the cell cycle and the inherited disorder ataxia-telangiectasi
  • radiation and breast cancer risk
  • genotoxicity of environmental agents in human mammary epithelial cells - a trigger for human breast cancer
  • organochlorine exposure and risk for breast cancer
  • diet and breast cancer - opportunities for prevention and intervention
  • perspectives and progress in development of breast cancer chemopreventive drugs
  • the molecular genetics of endometrial carcinoma
  • rodent model of reproductive tract leiomyomata - characterization and use in preclinical therapeutic studies
  • mechanisms of DES carcinogenicity - effects of the TGF (transgene)
  • estrogens and the genetic control of tumour growth
  • targeted antiestrogens
  • the metabolism and genotoxicity of tamoxifen
  • tamoxifen breast cancer prevention trial - an update.

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