Proceedings of the International Conference on Enzyme Pattern-Targated Chemotherapy held at Titisee, West Germany, May 2, 3 and 4, 1985
著者
書誌事項
Proceedings of the International Conference on Enzyme Pattern-Targated Chemotherapy held at Titisee, West Germany, May 2, 3 and 4, 1985
(Advances in enzyme regulation, v. 24)
Pergamon Press, 1985
- タイトル別名
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Enzyme Pattern-Targeted Chemotherapy
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内容説明・目次
内容説明
This volume concentrates on a central issue of great current interest in human and experimental chemotherapy, Enzyme Pattern-Targeted Chemotherapy. The topics include sessions on enzymes in strategic metabolic pathways and the drugs directed against the enzymes. The 27 articles by distinguished authors in this volume provide much new information that illuminates the experimental and clinical approaches of this fascinating aspect of chemotherapy.
目次
Dihydrofolate reductase as a target of chemotherapy, Chairman: F M Huennekens. IMP dehydrogenase-directed chemotherapy, Chairman: J G Cory. Polyamine synthetic enzymes as targets of chemotherapy, Chairman: R A Malt. Potentiation by alkylating agents of antimetabolite action, Chairman: S Eckhardt. Chemotherapy targeted against glutamine-utilizing enzymes, Chairman: G L Neil. Interaction of drugs with plasma membrane targets, Chairman: H Grunicke. Nucleic acid-targeted irreversible inhibitors, Chairman: E Reich. Enzymic targets of nucleoside analogs, Chairman: G B Elion. DNA polymerase and ribonucleotide reductase as targets for chemotherapy, Chairman: J Laszlo. Potentiation of antimetabolite action, Chairman: I Kline. Overview of the conference, F M Huennekens. Author index. Subject index.
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