Molecular pathogenesis of diabetes mellitus

書誌事項

Molecular pathogenesis of diabetes mellitus

volume editor, R.D.G. Leslie

(Frontiers of hormone research, vol. 22)

Karger, 1997

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注記

Includes bibliographical references and indexes

内容説明・目次

内容説明

Diabetes, already a prevalent disease worldwide, is increasing at a rate consistent with a global epidemic. The number of people affected is expected to double in the next 15 years to about 200 million. The disease is already one of the commonest causes of kidney failure, blindness and amputations. There is an urgent need to prevent either the development of these complications or the disease itself. Dramatic advances in our understanding of the pathogenesis of diabetes have led to the hope that diabetes can indeed be prevented. Several major international collaborative projects have been initiated with this aim. In this book, an outstanding group of international scientists provide a broad outline of the advances in basic science which underpin these projects. The book offers a clear, comprehensive and up-to-date account for the interested clinician and scientist, and will be invaluable as a reference book for those working in the field.

目次

  • Insulin-dependent diabetes mellitus: Aetiology and pathogenesis of insulin-dependent diabetes mellitus - a general view, F. Pociot et al
  • Genetic factors associated with insulin-dependent diabetes, S.C. Bain et al
  • Susceptibility in predisposing to insulin-dependent diabetes, H. Reijonen et al
  • Islet-related autoantigens and the pathogenesis of insulin-dependent diabetes mellitus - a 1996 update, V. Sepe et al
  • Role of T lymphocytes in the aetiology of insulin-dependent diabetes, M. Peakman
  • Lessons from animal models regarding pathogenesis of insulin-dependent diabetes mellitus, C. Boitard, C. Carnaud. Non-insulin-dependent diabetes mellitus: Etiology of non-insulin-dependent diabetes mellitus - a general overview , L.C. Groop
  • Genetic factors in the aetiology of non-insulin-dependent diabetes, A. Hattersley
  • Insulin secretion and the aetiology of non-insulin-dependent diabetes, D.R. Matthews, A. Clark
  • Mechanism of insulin action, J.A. Maassen, D.M. Ouwens.

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