Handbook of pharmaceutical granulation technology

著者

    • Parikh, Dilip M.

書誌事項

Handbook of pharmaceutical granulation technology

edited by Dilip M. Parikh

(Drugs and the pharmaceutical sciences, 81)

Dekker, c1997

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Integrating the basic principles and industrial practices of pharmaceutical granulation production, this book discusses technologies and demonstrates cost-effective approaches to manufacturing solid-dosage forms with content uniformity and consistent physical properties while complying with regulatory requirements. Specialists from pharmaceutical companies, academia, and the U.S. Drug Regulatory Affairs agency address current and changing practices in industrial drug granulation production. Text, charts, figures, and photographs illustrate the pros and cons of diverse methods and technologies for accurately achieving strong bonding of particles in tablets and capsules.

目次

Introduction, D. M. Parikh Theory of Granulation, L.L. Augsburger and M.K. Vuppala Drug Substance and Excipient Characterization, P.W.S. Heng and L.W.Chan Binders and Solvents, R.K. Khankari and J. Hontz Spray Drying as an Alternative Granulation Technique, F.V. Shaw Roller Compaction Technology, R.W. Miller High Shear Mixer Granulators, P. Holm Low Shear Granulators, T. Chirkot and C. W. Propst Batch Fluid Bed Granulation, D.M. Parikh, J.A. Bonck, and M. Mogavero Single-Pot Processing, T.P. Garcia and L.J. Lucisano Extrusion-Spheronization as a Granulation Technique, D.F. Erkoboni Continuous Granulation, M. Bonde Sizing of Granulation, G. S. Rekhi and M.K. Vuppala Granulation Characterization: Methods and Significance, C.M. Sinko Bioavailability and Granule Properties, S.S. Jambhekar Regulatory Issues in Granulation Processes, G.A. Hileman

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