Clinical trials : a methodologic perspective
著者
書誌事項
Clinical trials : a methodologic perspective
（Wiley series in probability and mathematical statistics, . Applied probability and statistics）
Wiley, c1997
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注記
"A Wiley-Interscience publication."
Bibliography: p. 536-575
Includes index
内容説明・目次
内容説明
This book gives the reader important accounts of basic statistical procedures used in clinical trials. It covers several areas of study, including biostatics, biomathematics, biometry and epidemiology. There is emphasis for trialists to learn good methodology while giving quality clinical treatment. Discusses and explores controversial issues such as ethics and offers pragmatic information regarding allegations of fraud or misconduct.
目次
- Preliminaries.
- Clinical Trials and Research.
- Ethical Considerations.
- Clinical Trials as Experimental Designs.
- Bias and Random Error.
- Objectives and Endpoints.
- Sample Size and Power.
- The Study Cohort.
- Treatment Allocation.
- Data--Dependent Stopping.
- Counting Patients and Events.
- Estimating Clinical Effects.
- Prognostic Factor Analyses.
- Reporting.
- Factorial Designs.
- Cross--Over Designs.
- Overviews/Meta--Analyses.
- Fraud and Misconduct.
- Data and Programs.
- Notation and Terminology.
- Comprehensive Bibliography.
- Index.
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