Molecular pharmacology : a short course

書誌事項

Molecular pharmacology : a short course

Terry Kenakin

Blackwell Science, c1997

大学図書館所蔵 件 / 6

この図書・雑誌をさがす

注記

Includes bibliographical references and index

内容説明・目次

内容説明

This text provides a brief introduction to general pharmacological principles and their use as experimental tools. By using receptor theory and molecular models, this text explores the mechanisms of drug response in body systems without using the body itself. Also discusses biostatistics as related to drug response quantification and optimization.

目次

  • 1. Biologic Systems and Definitions of Terms
  • 2. Dose-Response Curves
  • 3. Molecular Models of Drug-Receptor Interaction
  • 4. Human Receptors from Recombinant DNA
  • 5. Concentrations of Drugs in Tissues
  • 6. Agonism and Stimulus-Response Mechanisms
  • 7. Drug-Response Measurement Systems: Signal Strength, Stability, and Selectivity
  • 8. Drug Antagonism
  • 9. Statistical and Biologic Significance

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