Pharmaceutical enzymes

著者

    • Lauwers, Albert
    • Scharpé, Simon

書誌事項

Pharmaceutical enzymes

edited by Albert Lauwers, Simon Scharpé

（Drugs and the pharmaceutical sciences, 84）

Marcel Dekker, c1997

大学図書館所蔵 件 / 全4件

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注記

Includes index

内容説明・目次

内容説明

This well-integrated, one-of-a-kind resource offers comprehensive, interdisciplinary analyses of the entire pharmaceutical enzyme field-from molecular biology to clinical pharmacology. Highlights practical, previously unpublished information, immediately useful in industry and academic institutions! Emphasizing pharmacology and clinical impact, Pharmaceutical Enzymes discusses robust methods of measurement and evaluation reviews current knowledge on the bioavailability of pharmaceutical enzymes presents different chemical approaches to tailoring enzymes for the improvement of therapeutic effectiveness provides a step-by-step approach to molecular modeling describes recently introduced pharmaceutical products, including glucocerebrosidase for the treatment of Gaucher's disease and deoxyribonuclease for cystic fibrosis furnishes unique laboratory guidelines for the testing and quality control of pharmaceutical enzymes and more! With over 1200 bibliographic citations, figures, and tables, Pharmaceutical Enzymes is an indispensable, day-to-day reference for pharmacologists, enzymologists, microbiologists, organic and medicinal chemists and biochemists, biophysicists, biotechnologists, molecular and membrane biologists, immunologists, physiologists, pharmaceutical development managers, regulatory affairs personnel, and graduate-level students in these disciplines.

目次

Bioavailability of Pharmaceutical Enzymes Biopharmaceutical Aspects of Enzyme Absorption, Joseph Demeester The Endothelium Monolayer: Barrier to Enzyme and Drug Delivery, Felicia Antohe and Mark J. Pozansky Tailoring of Pharmaceutical Enzymes Enzyme-Albumin Conjugates: Advantages and Problems with Targeting, Mark J. Pozansky and Felicia Antohe Acyl Enzymes as Prodrugs, Fritz Markwardt Molecular Modeling of Pharmaceutical Important Targets, Gerritt Vriend, Dirk Hendriks, and Simon Scharpe Biochemical and Pharmacological Properties Cystein Proteinases from the Latez Carica papya L., Albert Lauwers and Phillippe M. Dekeyser Bromelein, Greet Vanhoof and Walter Cooreman Hyaluronidase, Joseph Demeester and Koen P. Vercruysse Exocrine Pancreas Substitution, Simon Scharpe, Wim Uyttenbroeck, and Nele Samyn I-Asparagnase - An Essential Antineoplastic Drug, Volker Wahn Macrophage-Targeted Glucocerebrosidase: A Therapeutically Effective Enzyme Replacement Product for Gaucher Disease, Norman Barton and Roscoe O. Brady Desoxyribonuclease, Ingrid De Meester and Stefan C. De Smedt Therapeutic Protein Inhibitors of Elastase, David Farley, Bernard Faller, and Hanspeter Nick Standardization and Methodology Good Standardization Practices, Albert Lauwers Assays, Joseph Demeester, Philippe M. Dekeyser, Nele Samyn, Ingrid Verhamme, Willy Sierens, and Albert Lauwers

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