Carbohydrates in drug design
Author(s)
Bibliographic Information
Carbohydrates in drug design
M. Dekker, c1997
Available at / 8 libraries
-
No Libraries matched.
- Remove all filters.
Note
Includes index
Description and Table of Contents
Description
Emphasizes the role of carbohydrates as anti-inflammatory, anticancer, antidiabetic, anticonvulsant, antibiotic and antiviral agents. The text covers chemical properties, biological functions, methodologies for synthesizing model compounds, conformational and steric effects, synthetic and enzymatic approaches, and the discovery and development of leads in emerging fields.
Table of Contents
- Carbohydrates as new and old targets for future drug design
- sialic acid analogues as potential antimicrobial agents
- sialoside mimetics and conjugates as anti-inflammatory agents and inhibitors of flu virus infections
- design and synthesis of cell adhesion carbohydrate ligands/inhibitors
- polysulfates - chemistry and potential as antiviral drugs
- carbohydrates with anticoagulant and antithrombotic properties
- heparin oligosaccharides - new analogues development and applications
- chemoenzymatic synthesis of optically active myo-inositol polyphosphate
- phosphatidylinositol-specific phospholipase C as target of rational drug design
- carba-sugars as indispensable units of aminocyclitol antibiotics and related biologically active compounds
- asazugars - chemistry and their biological activity as potential anti-HIV drugs
- sugar-modified pyrimidine nucleoside analogues with potential antiviral activity
- carbohydrate templates for the synthesis of 3'-hetero-nucleosides
- sugar-modified anthracyclines - a search for drugs able to overcome multidrug resistance
- lincomycin - an organic chemistry perspective
- fungal (1-3)-D-glucans - chemistry and antitumor activity.
by "Nielsen BookData"