Colony-stimulating factors : molecular and cellular biology
著者
書誌事項
Colony-stimulating factors : molecular and cellular biology
Marcel Dekker, c1997
2nd ed
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注記
Includes index
内容説明・目次
内容説明
Concentrating on proven data and adopting a structure-function approach, this text provides grounding for an intricate understanding of the molecular biology, physiological mechanisms, and routine clinical use in disease settings of colony-stimulating factors (CSFs). This edition includes eight additional chapters, with updates of recently-discovered and established CSFs, each indexed individually.
目次
- Overview: introduction to the haematopoietic system
- surrogate assays for haematopoietic stem cell activity
- receptors for haematopoietic regulators
- regulation of the cell cycle by kinases and cyclins
- gene organization and regulation
- cytokines and apoptosis - the mechanism of regulation of cell death
- haematopoietic microenvironments
- extracellular matrix- and membrane-bound cytokines
- transfection of stem cells and gene therapy. Colony-stimulating factor: granulocyte-macrophage colony-stimulating factor and its receptor
- granulocyte colony-stimulating factor
- human interleukin-3 - an overview
- macrophage colony-stimulating factor
- erythropoietic
- the role of interleukin-4 in normal and malignant human haematopoietic effects of interleukin-1
- kit-ligand-stem cell factor
- interleukin-5. Cytokines: macrophages inflammatory protein-1 alpha
- transforming growth factor-beta, tumour necrosis factor-alpha, and macrophage inflammatory protein-1 alpha are bidirectional regulators of haematopoietic cell growth
- leukaemia inhibitory factor
- interleukin-12 in haematopoiesis
- ex vivo expansion of haematopoietic stem and progenitor cells
- clinical use of cytokines.
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