Controlled drug delivery : challenges and strategies

著者

書誌事項

Controlled drug delivery : challenges and strategies

Kinam Park, editor

（ACS professional reference book）

American Chemical Society, c1997

大学図書館所蔵 件 / 全5件

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This volume discusses the challenges of creating controlled release dosage forms that will deliver new therapeutic agents based on high-molecular-weight molecules. It examines strategies for delivering drugs through resistant biological barriers and surveys a variety of topics, including drug targeting, self-regulated drug delivery, protein drug delivery, biosensors, cell and tissue engineering, new biomaterials, modeling methods, pharmacokinetics, and U.S. federal regulations.

目次

  • CONTROLLED DRUG DELIVERY: PAST, PRESENT, AND FUTURE
  • INTRACELLULAR DELIVERY AND TARGETING
  • 2. Intracellular Delivery of Peptides and Proteins
  • 3. DNA Delivery Vectors for Somatic Cell Gene Therapy
  • 4. Targetable Polymeric Drugs
  • 5. Particle Engineering of Biodegradable Colloids for Site-Specific Drug Delivery
  • 6. Site-Specific Drug Delivery in the Gastrointestinal Tract
  • SELF-REGULATED DRUG DELIVERY
  • 7. Feedback-Controlled Drug Delivery
  • 8. Stimuli-Sensitive Drug Delivery
  • 9. Sensocompatibility: Design Considerations for Biosensor-Based Drug Delivery Systems
  • DELIVERY OF PEPTIDE AND PROTEIN DRUGS
  • 10. Formulation of Proteins and Peptides
  • 11. Stability of Peptides and Proteins
  • 12. Peptide, Protein, and Vaccine Delivery from Implantable Polymeric Systems
  • 13. Oral Immunization Using Microparticles
  • 14. Peptide and Protein Delivery for Animal Health Applications
  • TISSUE ENGINEERING AND GENE THERAPY
  • 15. Protein Delivery by Microencapsulated Cells
  • 16. Tissue Engineering: Integrating Cells and Materials To Create Functional Tissue Replacements
  • 17. Drug Delivery Using Genetically Engineered Cell Implants
  • 18. Ribozymes as Antiviral Agents
  • NEW BIOMATERIALS FOR DRUG DELIVERY
  • 19. Pseudo-Poly(amino acid)s: Examples for Synthetic Materials Derived from Natural Metabolites
  • 20. Transductional Protein-Based Polymers as New Controlled-Release Vehicles
  • 21. Synthetically Designed Protein Polymer Biomaterials
  • 22. Biological Effects of Polymeric Drugs
  • 23. New Biodegradable Polymers for Medical Applications: Elastomeric Poly(phosphoester-urethane)s
  • 24. "Intelligent" Polymers
  • MODELING OF CONTROLLED DRUG DELIVERY
  • 25. Modeling of Self-Regulating Oscillatory Drug Delivery
  • 26. Modeling Studies of Future Controlled-Release Devices
  • 27. Computer Dynamics Simulation of Controlled Release
  • REGULATORY ISSUES
  • 28. Food and Drug Regulations for Controlled-Release Dosage Forms
  • 29. Pharmacodynamic and Pharmacokinetic/ Considerations in Controlled Drug Delivery

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