Molecular signaling and regulation in glial cells : a key to remyelination and functional repair

書誌事項

Molecular signaling and regulation in glial cells : a key to remyelination and functional repair

Jeserich...[et al.], eds

Springer, c1997

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注記

Proceedings of an international symposium held at Monastery Ohrbeck, Aug. 28-Sept. 2, 1995

Includes bibliographical references and index

内容説明・目次

内容説明

A survey of recent advances in the area of cellular and molecular biology of glial cells and their involvement in remyelination and functional repair in the CNS. A major part of the book deals with signalling paths within and among neural cells. Glial cells (astrocytes, oligodentrocytes, microglial cells) themselves release substantial amounts of cytokines, growth factors and other signalling molecules, which play an important role during injury and regeneration. Another signalling route between neurons and glial cells follows ion channels and neurotransmitter receptors. In addition to animal models, human oligodentrocytes in cell culture and in the human MS brain are characterized with respect to their immunocytochemistry and function.

目次

  • Part 1: Signalling for glial cells
  • cytokines, growth factors and their intracellular cascades
  • ion channels and neurotransmitter receptors. Part 2: Genes and proteins of myelin
  • structure, regulation and function. Part 3: Neural repair mechanisms in the CNS
  • cellular responses to injury
  • remyelination of lesions in Multiple Sclerosis
  • cell transplantation.

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