C-myc in B-cell neoplasia : 14th Workshop on Mechanisms in B-Cell Neoplasia
著者
書誌事項
C-myc in B-cell neoplasia : 14th Workshop on Mechanisms in B-Cell Neoplasia
(Current topics in microbiology and immunology, 224)
Springer-Verlag, c1997
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This text focuses on C-myc. The deregulation of C-myc transcription by retroviral insertion, chromosome translocation or gene amplification is a consistent oncogenic "mutation" in many forms of B-cell neoplasia. C-myc like several other genes involved in neoplasia is implicated in multiple aspects of cellular life. No single defined action has yet been established for myc. Research has been concentrated on defining the important functions and assigning these to various differentiation lineages. This book presents some perspectives on this complex problem.
目次
Regulation of the C-myc Gene.- Negative Regulation of C-myc.- C-myc Protein Interactions.- C-myc Protein Interactions: Max, Mad, Mxil.- Myc Targets.- C-myc in Lymphomagenesis.- C-myc in Multiple Myeloma Plasmacytomagenesis.
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