Cellular and molecular immunology
著者
書誌事項
Cellular and molecular immunology
Saunders, c1997
3rd ed
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The book provides a synthesis and critical analysis of advances in the field of cellular and molecular immunology, and aims to help the reader review the respective literature from the proper perspective. It offers material on the functional anatomy of immune responses, including regional immunity such as the cutaneous and mucosal immune systems. This third edition covers advances in the knowledge of the structures of molecules involved in immune responses, signal transduction, and lymphocyte apoptosis, and the development and functions of immune cells as revealed by the application of transgenic and knockout mouse models. The book is intended for medical school immunology courses, undergraduate and graduate immunology courses.
目次
Section I: Introduction to Immunology: General Properties of Immune Responses. Cells and Tissues of Immune System. Section II: Antigen Recognition and Lymphocyte Activation: Antibodies and Antigens. Maturation of B Lymphocytes and Expression of Immunoglobulin Genes. The Major Histocompatibility Complex. Antigen Processing and Presentation to T Lymphocytes. T Lymphocyte Antigen Recognition and Activation. T Cell Maturation in the Thymus. B Cell Activation and Antibody Production. Regulation of Immune Responses. Functional Anatomy of Immune Responses. Section III: Effector Mechanisms of Immune Responses. Cytokines. Effector Mechanisms of T Cell-Mediated Immune Reactions. Effector Mechanisms of Immunoglobulin E-Initiated Immune Reactions. The Complement System. Section IV: Immunity in Defense and Disease. Immunity to Microbes. Immune Responses to Tissue Transplants. Immunity to Tumours. Self-Tolerance and Autoimmunity. Immune-Mediated Tissue Injury and Disease. Congenital and Acquired Immunodeficiencies. Appendix: Principal Features of Known CD Molecules.
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