Bibliographic Information

Antiviral agents and human viral diseases

editors, George J. Galasso, Richard J. Whitley, Thomas C. Merigan

Lippincott-Raven Publishers, c1997

4th ed

Available at  / 8 libraries

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Note

Rev. ed. of: Antiviral agents and viral diseases of man. 3rd ed. c1990

Includes bibliographical references and index

Description and Table of Contents

Description

This resource synthesizes information on viral infectious diseases, and defines the advances in antiviral therapy that are influencing their natural history. This edition has an enhanced clinical focus and expanded coverage of the pharmacology, pre-clinical and clinical toxicology, clinical studies, and vaccines. All antiviral agents are covered - their chemical nature, pharmacology and mechanism of action. There are also discussions of the biology, epidemiology, pathogenesis, and natural history of human viral disease.

Table of Contents

  • Part 1 Basic biology - drug development: virus replication - target functions and events for virus-specific inhibitors
  • pathogenesis of viral infection
  • preclinical evaluation of antiviral agents - in vitro and animal testing
  • clinical drug development - human pharmacology, safety, and tolerance trials. Part 2 Laboratory diagnosis/clinical trials: laboratory diagnosis of viral infections
  • clinical trials methodology and statistical evaluation
  • major ocular viral infections
  • Varicella-Zoster virus infections
  • herpes simplex virus infections
  • human papilloma viruses and interferon therapy
  • respiratory viruses infections
  • viral infections of the gastrointestinal tract
  • antiviral therapy of viral hepatitis
  • viral infections of the central nervous system
  • chronic interuterine and perinatal infections
  • HIV and other human herpesvirus type 6 infections
  • cytomegalovirus and the immunocompromised patient
  • hantaviruses and other RNA haemorrhagic, encephalitic, and febrile disease viruses. Part 3 Prevention: immunization against viral diseases.

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