Cell signalling
Author(s)
Bibliographic Information
Cell signalling
Addison Wesley Longman, 1997
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Includes bibliographical references and index
Description and Table of Contents
Description
This text provides a concise and clear introduction to the molecular components which can be used by cells to signal either to each other, or to signal from their surface to their interiors. The text takes a generic approach, describing components of animals, plants and prokaryotes, and as such is not restricted to any particular field. Cell Signalling begins with an overview chapter, exploring concepts applicable to all areas of the subject. Subsequent chapters concentrate on the use of extracellular signals and their perception and then focus on intracellular components, such as G proteins, cAMP, inositol metabolism and calcium. Final chapters discuss free radical signals such as nitric oxide and hydrogen peroxide, and give examples of signalling pathways, such as those induced by insulin.
Table of Contents
1. Aspects of cellular signalling. 2. Extracellular signals: Hormones, cytokines and growth factors. 3. Detection of extracellular signals: Receptors. 4. Protein phosphorylation, kinases and phosphatases. 5. cAMP, adenylyl cyclase and the role of G proteins. 6. Inositol phosphate metabolism and the roles of other membrane lipids. 7. Intracellular calcium: Its control and role as an intracellular signal. 8. Nitric oxide, hydrogen peroxide and carbon monoxide. 9. Insulin and the signal transduction cascades it invokes. 10. Perception of our environment: Photoreception and the detection of chemicals.
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