Basic clinical radiobiology
著者
書誌事項
Basic clinical radiobiology
Arnold , Oxford University Press, 1997
2nd ed
大学図書館所蔵 全5件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
This is a basic teaching book for radiation oncologists, radiation physicists, and radiobiologists, setting out the biological basis of radiation therapy. Early chapters deal with essential areas of science, including cell proliferation in tumours and normal tissues, principles of radiation cell killing, theoretical and modelling approaches, and molecular aspects of radiobiology. Subsequent chapters deal with the applications of radiobiology to clinical radiotherapy. The principles of fractionalism are described in detail, leading to the rationale of current approaches to the improvement of radiotherapy schedules. Also discussed are efforts to beat hypoxia in tumours, brachytherapy, the principles and use of particle beams, the combination of radiotherapy and chemotherapy, hyperthermia, targeted radiotherapy, and current efforts to individualize treatment with radiation therapy. This second edition has been updated and expanded to include advances in molecular growth. Each chapter concludes with a list of key points, and there are frequent cross-references between chapters.
目次
- Introduction - the significance of radiobiology for radiotherapy
- the growth of tumours
- cell proliferation in tumours
- proliferative and cellular organization of normal tumours
- radiation response and tolerance of normal tissues
- clonogenic cells and the concept of cell survival
- models of radiation cell killing
- DNA damage and cell killing
- genetic control for the cellular response to ionizing radiation
- dose-response relationships in radiotherapy
- clinical manifestations of normal-tissue damage
- time-dose relationships in radiotherapy
- the linear-quadratic approach to fractionation and calculation of isoeffect relationships
- hyperfractionation and accelerated radiotherapy
- the oxygen effect
- overcoming hypoxic radioresistance
- the radiobiology of tumours
- the dose-rate effect - brachytherapy
- particle beams in radiotherapy
- combination of radiotherapy and chemotherapy - principles
- combination of radiotherapy and chemotherapy - clinical application and evaluation
- re-treatment tolerance of normal tissues
- hyperthermia
- targeted radiotherapy
- individualization of radiotherapy.
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