Multiple myeloma
著者
書誌事項
Multiple myeloma
Arnold , Oxford Unversity Press, 1996
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Multiple myeloma has been one of the most studied malignancies since its discovery in the mid-nineteenth century. During the last decade, knowledge about the disease has advanced rapidly.
'Multiple Myeloma' provides a comprehensive and authoritative account of the condition emphasising current diagnosis and management. The book examines the impact that sophisticated new techniques (such as immunophenotyping, cell sorting, cytogenetics, growth-factor analysis, and molecular biology) have had on our understanding of the disease. New treatment methods have not been introduced without difficulties, and the risk factors of intensive antibacterial and antiviral therapies and transplantation are fully discussed.
The contributors are all recognised experts in the field with 'hands on' experience, making this invaluable reading for oncologists and haematologists.
目次
Preface
History of multiple myeloma
Epidemiology and incidence of plasma cell neoplasms
Basic concepts - the plasma cell in multiple myeloma
Immunoglobulins in multiple myeloma
Human myeloma induced bone changes
Chromosome abnormalities
Oncogenes related to multiple myeloma
Growth factors in the pathogenesis of multiple myeloma
Monoclonal gammopathies of undetermined significance (MGUS)
Clinical features and staging
Principles of chemotherapy and radiotherapy
Treatment of refractory multiple myeloma with cytoxic therapy and radiation therapy
Use of interferon in the treatment of multiple myeloma
Cytokines in the treatment of multiple myeloma
Autologous transplantation in multiple myeloma
Bone marrow transplantation with syngeneic or allogeneic marrow in multiple myeloma
Complications and supportive treatment
Index
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