HLA and disease - the molecular basis : proceedings of a symposium held at the Royal Danish Academy of Sciences and Letters, August 4-8, 1996
著者
書誌事項
HLA and disease - the molecular basis : proceedings of a symposium held at the Royal Danish Academy of Sciences and Letters, August 4-8, 1996
（Alfred Benzon Symposium, 40）
, c1997
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注記
Includes bibliographies
内容説明・目次
内容説明
These symposium papers aim to generate an overview of the different components involved in the trimolecular interaction, with special emphasis on genetics, structure, function, animal models and treatment of human autoimmune disorders. Immune-specific intervention in autoimmune disorders will require a detailed molecular understanding of the trimolecular interaction between HLA class II molecues, peptide antigens and T-cell receptors.
目次
- HLA molecules - genes and structures
- antigen processing
- peptide binding
- T-cell recognition
- thymic selection and tolerance
- HLA and disease
- pathogenesis of autoimmune disorders
- towards therapy of autoimmune disorders.
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