Therapeutic agents

著者

• Burger, Alfred
• Wolff, Manfred E.

書誌事項

Therapeutic agents

edited by Manfred E. Wolff

（A Wiley-Interscience publication, . Burger's medicinal chemistry and drug discovery / [Alfred Burger] ; v. 2-5）

Wiley, 1996-1997

• [1]
• [2]
• [3]
• [4]

タイトル別名

Medicinal chemistry and drug discovery

Medicinal chemistry

注記

中位の書誌の版は5th ed.

Includes bibliographical references and index

内容説明・目次

巻冊次

[1] ISBN 9780471575573

内容説明

Medicinal chemistry is the branch of chemistry that relates to the discovery, design and development of therapeutic chemical agents, or drugs, for use in clinical and veterinary medicine. It deals with the relationship between chemical structure and biological activity. The chemical concepts of this field has permeated fields of biology, genetics, medicine, toxicology and pest control. Since the early 1980s, the pace of drug discovery has rapidly accelerated and many new methods are being used. Volume 2 is a survey of cholinergic drugs, cardiac drugs and chemotherapeutics.

目次

• Gastrointestinal drugs - cholinergics
• anticholinergic drugs
• gastric H+/K+ ATPasc inhibitors
• cardiovascular drugs: cardiac drugs
• antihypertensive agents
• phenoxyacetic acid uricosuric diuretics
• diuretic and uricosuric agents
• chemotherapeutic agents: quinolonc
• glycopeptide
• marcrolides
• and other nonlactam antibiotics
• sulfonamides and sulfones
• animycobacterial agents
• antifungal agents.

巻冊次

[2] ISBN 9780471575580

内容説明

The pace of drug discovery has accelerated and many methods are being used. Volume 3 of this text features authoritative and comprehensive surveys of central nervous system, endocrine and immune system drugs. The text is updated and expanded and all chapters have been revised to reflect the increased biological understanding of each of the disease categories covered, which has come about through techniques in molecular biology. There is material on immune system modifiers, antipsychotic/antianxiety and antidepressant drugs.

目次

• Partial table of contents:
• CNS DRUGS
• General Anesthetics (K. Miller)
• Antiparkinsonism Drugs (V. Vernier)
• Sedatives and Hypnotics (J. Vida)
• Anticonvulsants (I. Edafiogho & K. Scott)
• Agents Used in Neurodegenerative Disorders (J. Adams)
• Analgesics (J. Aldrich)
• ENDOCRINE DRUGS
• Male Sex Hormones and Analogs (R. Bruggemeir)
• Antiallergic Agents (D. Connor & P. Unangst)
• Retinoids (M. Dawson)
• Insulin Analogs (J. Galloway & R. Chance)
• Index.

巻冊次

[3] ISBN 9780471575597

内容説明

This volume covers fields such as rational drug design, computational modelling, peptidomimetics and biotechnology. Particular attention is paid to product development questions which should be considered early in the discovery phase. The management of drug discovery, accessing and protecting information, and intellectual property are discussed, and questions of ADME, toxicity, drug allergy, and clinical trial issues are reviewed. The book also includes advances made in the structural biology of drug action.

目次

• Radiosensitizers and radioprotective agents
• agents for myocardial infarction
• endogenous vasoactive peptides
• hematopoietic agents
• anitcoagulants, anthrombotics, and hemostatics
• synthetic antibacterial agents
• lactam antibiotics
• anthelmintic agents
• antiamebic agents
• chemotherapy of aftican trypansomiasis
• antimalarials
• female sex hormones and analogs
• agents affecting the immune response.

巻冊次

[4] ISBN 9780471575603

内容説明

Thoroughly updated and expanded, this edition presents additional information on central nervous system, endocrine and immune system drugs. All chapters are updated to reflect the increased biological understanding of each disease category covered. New material to this edition covers the immune system modifiers, antipsychotic/antianxiety and antidepressant drugs.

目次

• CNS DRUGS: Local Anaesthetics
• Antipsychotic Agents
• Antidepressant Agents. Anorexigenics. Cognition Enhancers and Agents for Alzheimer's Disease. Agents for Ischaemic Injury and Reperfusion Injury. Agents Used in Neurodegenerative Disorders. ENDOCRINE & IMMUNE REGULATORS: Peptide and Protein Hormones. Blood Calcium Regulators and Agents for Osteoporosis. Calciotropic Hormones. Female Sex Hormones and Analogs. Agents Affecting Fertility. Agents Affecting the Immune Response. Agents Affecting the Action of Prostaglandins. Agents Affecting the Action of Leukotrienes and Thromboxanes. Nonsteroidal Anti-inflammatory Agents. Anti-inflammatory Steroids. Histamine H1 Antagonists. Histamine H1 Antagonists, Ocular. Gene Mimetic Substances.

「Nielsen BookData」 より

詳細情報

• NII書誌ID(NCID): BA33246644
• ISBN:
  • 0471575577
  • 0471575585
  • 0471575593
  • 0471575607
• LCCN: 94012687
• 出版国コード: us
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: New York
• ページ数/冊数: 4 v.
• 大きさ: 26 cm
• 分類:
  • LCC : RS403
  • DC20 : 615/.19
• 件名:
  • LCSH : Pharmaceutical chemistry
• 親書誌ID:
  • BA00493885