Anti-AIDS drug development : challenges, strategies, and prospects

Bibliographic Information

Anti-AIDS drug development : challenges, strategies, and prospects

edited by Prem Mohan, Masanori Baba

Harwood Academic, 1995

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

This book covers the major arenas of drug development, providing understanding of the pros and cons of the various efforts of chemists and biologists to explore newer antiviral targets for HIV replication and to look for and design molecules that will have minimal toxicities.

Table of Contents

1. From Anti-HIV Agents to Anti-AIDS Chemotherapy: A Critical Appraisal 2. Nucleosides and Derivatives 3. Iminosugar a-Glucosidase Inhibitors 4. Inhibition of HIV Protease: A Strategy for the Treatment of AIDS 5. Regulatory Proteins of Hum an Immunodeficiency 6. CD4 Mimetics and Analogs 7. Antisense Oligonucleotide Approach for Therapy of AIDS 8. Resistance to Anti-HIV Agents for Anti-AIDS Drug Development 9. Anti-HIV Drug Test Systems: Significance and Limitations 10. Plant-derived Anti-HIV Agents 11. HIV-1-specific Reverse Transcriptase Inhibitors 12. Small and Large Polyanionic Derivatives

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