CiNii 図書 - Manual of clinical laboratory immunology

The much-awaited new edition of this classic reference manual features the latest on standard and cutting-edge immunological tests and procedures in clinical laboratory immunology. The best features of earlier editions have remained in this update, including a step-by-step interpretive approach to

PART I: GENERAL METHODS
SECTION A: IMMUNOLOGICAL METHODS
Introduction
Agglutination Immunoassays
Light-Scattering Immunoassays
Enzyme-Linked Immunoassays
A Model System for Radioimmunoassays: Digoxin Reference Method
Fluorescence Immunoassays
Chemiluminescence Immunoassays
Immunofixation and Immunoblotting
Clinical Indications for Electrophoresis and Immunofixation
SECTION B: MOLECULAR BIOLOGY METHODS
Introduction to Molecular Methodology
Choosing Appropriate Methodologies in the Clinical Environment: Immunological Techniques versus Molecular Methods
Keys to Successful In Situ PCR
SECTION C: IMMUNOGLOBULIN METHODS
Introduction
Immunoglobulin Quantitation
Immunoglobulin Genes
Immunochemical Characterization of Immunoglobulins
SECTION D: COMPLEMENT, IMMUNE COMPLEXES, AND CRYOGLOBULIN
Introduction
Complement Tests
Complement Activation
Complement Receptors
Genetic Typing of the Complement System
Tests for Circulating Immune Complexes and Autoantibodies to C 1 q
Cryoglobulins
SECTION E: IMMUNE CELL PHENOTYPING AND FLOW CYTOMETRIC ANALYSIS
Introduction
Immunophenotyping by Flow Cytometry
Functional Assays by Flow Cytometry
Flow Cytometric Analysis of DNA Content in Solid Tumors
Emerging Clinical Applications of Flow Cytometry: Microbiology and Parasitology
SECTION F: IMMUNE CELL ASSAYS
Introduction
Delayed Hypersensitivity Skin Testing
Cryopreservation of Peripheral Blood Mononuclear Cells
T-Lymphocyte Activation
Cytolytic Cell Functions
Methods for Identification of the T-Cell Antigen Receptor
Lymphocyte Proliferation
Phagocytic Cell Functions I: Oxidation and Chemotaxis
Phagocytic Cell Functions II: Adhesion and Phagocytosis
Methods for Analysis of Apoptosis by Flow Cytometry
SECTION G: IMMUNE CELL PRODUCTS
Introduction
Cytokines and Immune Cell Products
Development and Use of Cytokine and Growth Factor Potency Standards
Measuring Cell Adhesion Molecules
SECTION H: IMMUNOHISTOLOGY AND IMMUNOPATHOLOGY
Introduction
Immunohistochemistry: Principles and Practice
Immunohistochemistry in the Diagnosis of Solid Tumors
Immunohistochemistry in the Diagnosis of Lymphomas
Prognostic Markers in Immunohistochemistry
In Situ Hybridization as an Adjunct Method with Immunohistochemistry
Immunofluorecence Methods for Diagnosis of Renal and Skin Diseases
Immunoelectron Microscopy in Diagnostic Pathology
PART II: IMMUNOLOGIC DIAGNOSIS AND MONITORING OF DISEASE
SECTION I: INFECTIOUS DISEASES CAUSED BY BACTERIA, MYCOPLASMAS, CHLAMYDIAE, AND RICKETTSIAE
Introduction
Immune Response to Streptococcal Antigens: Diagnostic Methods
Haemophilus influenzae Type b, Neisseria meningitidis, Streptococcis pneumoniae, and Corynebacterium diptheriae Vaccines
Clostridium tetani: Immune Response and Diagnostic Methods
Immunologic Methods for Diagnosis of Infections by Gram-Negative Cocci
Immunologic Methods for the Diagnosis of Infections Caused by Diarrheagenic Members of the Families Enterobacteriaceae and Vibrionaceae
Serodiagnosis of Helicobacter pylori Infection
Detection of Antibodies to Legionella spp.
Immunologic Methods for Diagnosis of Spirochetal Diseases
Lyme Disease: Serodiagnosis of Borrelia burgdorferi Sensu Lato Infection
Immunological Procedures for Diagnosis of Tuberculosis and Leprosy
Nocardiae and Agents of Actinomycosis
Mycoplasma Infection: Immunologic and Molecular Biologic Diagnostic Techniques
Chlamydiae
Immunoserology of Rickettsiae
SECTION J: MYCOTIC AND PARASITIC DISEASES
Introduction to Clinical Immunomycology and Clinical Immunoparasitology
Clinical Immunoparasitology
Clinical Immunomycology
SECTION K: VIRAL DISEASES
Introduction
Rapid Viral Diagnosis
Antibody-Enhanced Detection of Viruses in Cell Cultures
Herpes Simplex Virus
Varicella-Zoster Virus
Epstein-Barr Virus
Cytomegalovirus
Human Herpesviruses 6 and 7
Papovaviruses
Adenoviruses
Parvovirus B 1 9
Influenza Viruses
Respiratory Syncytial Virus and Parainfluenza Viruses
Measles and Mumps
Rubella Virus
Enteroviruses
Hepatitis Viruses
Enzyme Immunoassays for Detection of Rotavirus Antigen and Antibody
Arboviruses
Hantaviruses
Marburg Virus, Ebola Virus and the Arenaviruses
Rabies Virus
SECTION L: HUMAN IMMUNODEFICIENCY VIRUS
Introduction
Immunologic Evaluation of Patients with Human Immunodeficiency Virus Infection
Quantitation of Viremia in Human Immunodeficiency Virus Infection
Isolation and Detection of Human Immunodefiency Virus
Principles and Procedures of Human Immunodeficiency Virus Serodiagnosis
Sequence Analysis of Human Immunodeficiency Virus Type 1 Haplotypes
SECTION M: IMMUNODEFICIENCY DISEASES
Introduction
Genetics and Inherited Immunodeficiency Diseases and Diagnostic Techniques
Combined B- and T-Cell Deficiencies
Investigation of Signal Transduction Defects
Primary Antibody Deficiencies in Children and Adults
Inherited and Acquired C 1 -Inhibitor Deficiency
Genetically Determined Deficiencies of the Complement System: C 1 , C 4, C 2, and C 3
Alternative Pathway and Late Complement Component Deficiencies
Neutropenia and Neutrophil Defects
SECTION N: ALLERGIC DISEASES
Introduction
Quantitation and Standardization of Allergens
In Vivo Diagnostic Allergy Testing Methods
Immunological Tests for Diagnosis and Management of Human Allergic Disease: Total and Allergen-Specific IgE and Allergen-Specific IgG
Tests for Immunological Reactions to Drugs and Occupational Allergens
Assay Methods for the Measurement of Mediators and Markers of Allergic Inflammation
Immunological Tests for Evaluation of Hypersensitivity Pneumonitis and Allergic Bronchopulmonary Aspergillosis
SECTION O: SYSTEMIC AUTOIMMUNE DISEASES
Introduction
Immunofluorescent Antinuclear Antibody Tests
Detection of Autoantibodies to Ribonucleoprotein Part icles by Immunoblotting
Enzyme-Linked Immunosorbent Assays for Antibodies to Native DNA, Histones, and (H 2A-H 2B)-DNA
Rheumatoid Factors
Antiphospholipid Antibodies
Antineutrophil Cytoplasmic Antibodies
Autoantibodies to Complement Components
SECTION P: ORGAN-LOCALIZED AUTOIMMUNE DISEASES
Introduction
Endocrinopathies
Detection of Autoantibodies in Myasthenia Gravis and Lambert-Eaton Myasthenic Syndrome
Detection of Antimitochondrial Autoantibodies in Primary Biliary Cirrhosis and Liver-Kidney Microsomal Antibodies in Autoimmune Hepatitis
Skin Diseases
Cardiovascular Diseases
Kidney and Lung Disease Mediated by Glomerular Basement Membrane Antibodies: Detection by Western Blot Analysis
Human Spermatozoa Antibodies: Detection and Clinical Significance
Autoimmune Hemolytic Anemias
Autoimmune Thrombocytopenia
SECTION Q: CANCER
Introduction
Human Tumor Antigens Recognized by T Lymphocytes
Cancer Vaccines
Cancer Genes and Early Cancer Detection
Malignancies of the Lymphoid and Histiocytic Systems
Monitoring of Immunologic Therapies
SECTION R: TRANSPLANTATION IMMUNOLOGY AND IMMUNOGENETICS
Introduction: Genes in the Human Major Histocompatibility Complex Relevant to Immune Regulation and Transplantation and Other Clinical Applications
Histocompatibility Testing by Immunologic Methods: Cellular Assays
Histocompatability Testing by Immunologic Methods: Humoral Assays
HLA Typing by Molecular Methods
Pre-Transplant Histocompatibility Assessment for Solid Organ Transplantation
Immunological Characterization of Solid Organ Graft Recipients
Histocompatibility Assessment in Bone Marrow Transplantation
Statistical Analysis and Applications of HLA Population Data
Principles and Applications of Genetic Identification
PART III: ADMINISTRATION
SECTION S: LABORATORY MANAGEMENT
Introduction
Establishment and Verification of Reference Values
Standardization of Immunoassay Methodologies
Quality Assurance
Planning Statistical Quality Control Procedures
Interlaboratory Proficiency Testing in Laboratory Immunology
Clinical Significance and Cost-Effectiveness of Clinical Immunology Testing
Laboratory Safety

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Manual of clinical laboratory immunology

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