Manual of clinical laboratory immunology
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Bibliographic Information
Manual of clinical laboratory immunology
ASM Press, c1997
5th ed
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Note
Includes bibliographical references and index
Description and Table of Contents
Description
The much-awaited new edition of this classic reference manual features the latest on standard and cutting-edge immunological tests and procedures in clinical laboratory immunology. The best features of earlier editions have remained in this update, including a step-by-step interpretive approach to
Table of Contents
- PART I: GENERAL METHODS
- SECTION A: IMMUNOLOGICAL METHODS
- Introduction
- Agglutination Immunoassays
- Light-Scattering Immunoassays
- Enzyme-Linked Immunoassays
- A Model System for Radioimmunoassays: Digoxin Reference Method
- Fluorescence Immunoassays
- Chemiluminescence Immunoassays
- Immunofixation and Immunoblotting
- Clinical Indications for Electrophoresis and Immunofixation
- SECTION B: MOLECULAR BIOLOGY METHODS
- Introduction to Molecular Methodology
- Choosing Appropriate Methodologies in the Clinical Environment: Immunological Techniques versus Molecular Methods
- Keys to Successful In Situ PCR
- SECTION C: IMMUNOGLOBULIN METHODS
- Introduction
- Immunoglobulin Quantitation
- Immunoglobulin Genes
- Immunochemical Characterization of Immunoglobulins
- SECTION D: COMPLEMENT, IMMUNE COMPLEXES, AND CRYOGLOBULIN
- Introduction
- Complement Tests
- Complement Activation
- Complement Receptors
- Genetic Typing of the Complement System
- Tests for Circulating Immune Complexes and Autoantibodies to C 1 q
- Cryoglobulins
- SECTION E: IMMUNE CELL PHENOTYPING AND FLOW CYTOMETRIC ANALYSIS
- Introduction
- Immunophenotyping by Flow Cytometry
- Functional Assays by Flow Cytometry
- Flow Cytometric Analysis of DNA Content in Solid Tumors
- Emerging Clinical Applications of Flow Cytometry: Microbiology and Parasitology
- SECTION F: IMMUNE CELL ASSAYS
- Introduction
- Delayed Hypersensitivity Skin Testing
- Cryopreservation of Peripheral Blood Mononuclear Cells
- T-Lymphocyte Activation
- Cytolytic Cell Functions
- Methods for Identification of the T-Cell Antigen Receptor
- Lymphocyte Proliferation
- Phagocytic Cell Functions I: Oxidation and Chemotaxis
- Phagocytic Cell Functions II: Adhesion and Phagocytosis
- Methods for Analysis of Apoptosis by Flow Cytometry
- SECTION G: IMMUNE CELL PRODUCTS
- Introduction
- Cytokines and Immune Cell Products
- Development and Use of Cytokine and Growth Factor Potency Standards
- Measuring Cell Adhesion Molecules
- SECTION H: IMMUNOHISTOLOGY AND IMMUNOPATHOLOGY
- Introduction
- Immunohistochemistry: Principles and Practice
- Immunohistochemistry in the Diagnosis of Solid Tumors
- Immunohistochemistry in the Diagnosis of Lymphomas
- Prognostic Markers in Immunohistochemistry
- In Situ Hybridization as an Adjunct Method with Immunohistochemistry
- Immunofluorecence Methods for Diagnosis of Renal and Skin Diseases
- Immunoelectron Microscopy in Diagnostic Pathology
- PART II: IMMUNOLOGIC DIAGNOSIS AND MONITORING OF DISEASE
- SECTION I: INFECTIOUS DISEASES CAUSED BY BACTERIA, MYCOPLASMAS, CHLAMYDIAE, AND RICKETTSIAE
- Introduction
- Immune Response to Streptococcal Antigens: Diagnostic Methods
- Haemophilus influenzae Type b, Neisseria meningitidis, Streptococcis pneumoniae, and Corynebacterium diptheriae Vaccines
- Clostridium tetani: Immune Response and Diagnostic Methods
- Immunologic Methods for Diagnosis of Infections by Gram-Negative Cocci
- Immunologic Methods for the Diagnosis of Infections Caused by Diarrheagenic Members of the Families Enterobacteriaceae and Vibrionaceae
- Serodiagnosis of Helicobacter pylori Infection
- Detection of Antibodies to Legionella spp.
- Immunologic Methods for Diagnosis of Spirochetal Diseases
- Lyme Disease: Serodiagnosis of Borrelia burgdorferi Sensu Lato Infection
- Immunological Procedures for Diagnosis of Tuberculosis and Leprosy
- Nocardiae and Agents of Actinomycosis
- Mycoplasma Infection: Immunologic and Molecular Biologic Diagnostic Techniques
- Chlamydiae
- Immunoserology of Rickettsiae
- SECTION J: MYCOTIC AND PARASITIC DISEASES
- Introduction to Clinical Immunomycology and Clinical Immunoparasitology
- Clinical Immunoparasitology
- Clinical Immunomycology
- SECTION K: VIRAL DISEASES
- Introduction
- Rapid Viral Diagnosis
- Antibody-Enhanced Detection of Viruses in Cell Cultures
- Herpes Simplex Virus
- Varicella-Zoster Virus
- Epstein-Barr Virus
- Cytomegalovirus
- Human Herpesviruses 6 and 7
- Papovaviruses
- Adenoviruses
- Parvovirus B 1 9
- Influenza Viruses
- Respiratory Syncytial Virus and Parainfluenza Viruses
- Measles and Mumps
- Rubella Virus
- Enteroviruses
- Hepatitis Viruses
- Enzyme Immunoassays for Detection of Rotavirus Antigen and Antibody
- Arboviruses
- Hantaviruses
- Marburg Virus, Ebola Virus and the Arenaviruses
- Rabies Virus
- SECTION L: HUMAN IMMUNODEFICIENCY VIRUS
- Introduction
- Immunologic Evaluation of Patients with Human Immunodeficiency Virus Infection
- Quantitation of Viremia in Human Immunodeficiency Virus Infection
- Isolation and Detection of Human Immunodefiency Virus
- Principles and Procedures of Human Immunodeficiency Virus Serodiagnosis
- Sequence Analysis of Human Immunodeficiency Virus Type 1 Haplotypes
- SECTION M: IMMUNODEFICIENCY DISEASES
- Introduction
- Genetics and Inherited Immunodeficiency Diseases and Diagnostic Techniques
- Combined B- and T-Cell Deficiencies
- Investigation of Signal Transduction Defects
- Primary Antibody Deficiencies in Children and Adults
- Inherited and Acquired C 1 -Inhibitor Deficiency
- Genetically Determined Deficiencies of the Complement System: C 1 , C 4, C 2, and C 3
- Alternative Pathway and Late Complement Component Deficiencies
- Neutropenia and Neutrophil Defects
- SECTION N: ALLERGIC DISEASES
- Introduction
- Quantitation and Standardization of Allergens
- In Vivo Diagnostic Allergy Testing Methods
- Immunological Tests for Diagnosis and Management of Human Allergic Disease: Total and Allergen-Specific IgE and Allergen-Specific IgG
- Tests for Immunological Reactions to Drugs and Occupational Allergens
- Assay Methods for the Measurement of Mediators and Markers of Allergic Inflammation
- Immunological Tests for Evaluation of Hypersensitivity Pneumonitis and Allergic Bronchopulmonary Aspergillosis
- SECTION O: SYSTEMIC AUTOIMMUNE DISEASES
- Introduction
- Immunofluorescent Antinuclear Antibody Tests
- Detection of Autoantibodies to Ribonucleoprotein Part icles by Immunoblotting
- Enzyme-Linked Immunosorbent Assays for Antibodies to Native DNA, Histones, and (H 2A-H 2B)-DNA
- Rheumatoid Factors
- Antiphospholipid Antibodies
- Antineutrophil Cytoplasmic Antibodies
- Autoantibodies to Complement Components
- SECTION P: ORGAN-LOCALIZED AUTOIMMUNE DISEASES
- Introduction
- Endocrinopathies
- Detection of Autoantibodies in Myasthenia Gravis and Lambert-Eaton Myasthenic Syndrome
- Detection of Antimitochondrial Autoantibodies in Primary Biliary Cirrhosis and Liver-Kidney Microsomal Antibodies in Autoimmune Hepatitis
- Skin Diseases
- Cardiovascular Diseases
- Kidney and Lung Disease Mediated by Glomerular Basement Membrane Antibodies: Detection by Western Blot Analysis
- Human Spermatozoa Antibodies: Detection and Clinical Significance
- Autoimmune Hemolytic Anemias
- Autoimmune Thrombocytopenia
- SECTION Q: CANCER
- Introduction
- Human Tumor Antigens Recognized by T Lymphocytes
- Cancer Vaccines
- Cancer Genes and Early Cancer Detection
- Malignancies of the Lymphoid and Histiocytic Systems
- Monitoring of Immunologic Therapies
- SECTION R: TRANSPLANTATION IMMUNOLOGY AND IMMUNOGENETICS
- Introduction: Genes in the Human Major Histocompatibility Complex Relevant to Immune Regulation and Transplantation and Other Clinical Applications
- Histocompatibility Testing by Immunologic Methods: Cellular Assays
- Histocompatability Testing by Immunologic Methods: Humoral Assays
- HLA Typing by Molecular Methods
- Pre-Transplant Histocompatibility Assessment for Solid Organ Transplantation
- Immunological Characterization of Solid Organ Graft Recipients
- Histocompatibility Assessment in Bone Marrow Transplantation
- Statistical Analysis and Applications of HLA Population Data
- Principles and Applications of Genetic Identification
- PART III: ADMINISTRATION
- SECTION S: LABORATORY MANAGEMENT
- Introduction
- Establishment and Verification of Reference Values
- Standardization of Immunoassay Methodologies
- Quality Assurance
- Planning Statistical Quality Control Procedures
- Interlaboratory Proficiency Testing in Laboratory Immunology
- Clinical Significance and Cost-Effectiveness of Clinical Immunology Testing
- Laboratory Safety
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