Artificial self-assembling systems for gene delivery

著者

    • Felgner, Philip L.
    • Cambridge Healthtech Institute

書誌事項

Artificial self-assembling systems for gene delivery

Philip L. Felgner, editor ... [et al.]

(Conference proceedings series)

American Chemical Society, c1996

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注記

"Developed from two conferences sponsored by Cambridge Healthtech Institute, September 28-29, 1995, in Wakefield, Massachusetts, and October 10-11, 1995, in Washington, D.C."

Includes bibliographical references and indexes

内容説明・目次

内容説明

Discusses recent advances in artificial self-assembling systems, including retrotransposon vectors, hairpin ribozymes, triple-helix-forming oligonucleotides, liposome-mediated transfection, and photonic nanostructures. Addresses developing efficient synthetic vectors such as modular self-assembling systems mimicking important features of viral vectors. Presents new developments in synthetic self-assembling gene delivery systems, including innovations in nonviral systems, targeting nucleic acids, ligand-polylysine mediated transfer, dendrimer-mediated transfection, cationic liposomes, and polylysine DNA complexes.

目次

  • Synthetic Retrotransposon Vectors and Gene Targeting
  • A New Retroviral Vector and a New Method To Target Homologous Recombination in Mammalian Cells
  • Development of the Hairpin Ribozyme as a Gene Therapy Approach to Human Immunodeficiency Virus Type-1 Infection
  • Replicating Plasmid Vectors for Cancer Gene Therapy
  • Gene Targeting Using Triple-Helix-Forming Oligonucleotides
  • Effects of Lipololysaccahrides on Liposome-Mediated Transfection and the Consequence for DNA Preparation for Gene Therapy
  • The Application of Electronic Pulse Delivery in Gene Therapy: Progress and Perspectives
  • Self-Assembling DNA Photonic Nanostructures
  • Controllable Gene Therapy Using Nonviral Systems
  • Progress in Targeting Nucleic Acids to the Liver
  • Advances in Receptor-Mediated Gene Transfer into Cells In Vitro and In Vivo
  • Ligand-Polylysine Mediated Gene Transfer
  • Efficient Transfer of Genetic Material into Mammalian Cells Using Polyamidoamine Dendrimers as Synthetic Vectors: Dendrimer-Mediated Transfection
  • The Proton Sponge: A Trick the Viruses Did Not Exploit
  • Biomaterials for Gene Transfer: Self-Assembling Nanostructured Aquasomes
  • Gene Transfer by Liposome-Entrapped Polycation-Condensed DNA: LPDI and LPDII
  • Gene Transfer into Mammalian Cells Using Synthetic Cationic Lipids

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