Therapeutic protein and peptide formulation and delivery
Author(s)
Bibliographic Information
Therapeutic protein and peptide formulation and delivery
（ACS symposium series, 675）
American Chemical Society, c1997
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"Developed from a symposium sponsored by the Division of Biochemical Technology at the 211th National Meeting of the American Chemical Society, New Orleans, Louisiana, March 24-28, 1996."--T.p. verso
Includes bibliographical references and index
Description and Table of Contents
Description
This volume reviews protein stability and the analytical and biophysical characterization of proteins. It emphasizes drug delivery approaches, especially local delivery through the skin. Including both academic and industrial perspectives from such companies as Genentech, Amgen, and Merck, the book also discusses novel drug delivery polymers and the development of pharmaceutical protein formulations.
Table of Contents
- 1: Zahra Shahrokh: Developing Pharmaceutical Protein Formulations: Assumptions and Analytical Tools
- 2: Henry R. Costantino, Stanley Liauw, Samir Mitragotri, Robert Langer, Alexander M. Klibanov, and Victoria Sluzky: The Pharmaceutical Development of Insulin: Historical Perspectives and Future Directions
- 3: Leonard N. Bell: Stability of the Dipeptide Aspartame in Solids and Solutions
- 4: Christian Sch "oneich, Fang Zhao, Jian Yang, and Brian L. Miller: Mechanisms of Methionine Oxidation in Peptides
- 5: David M. Barbieri, Martin C. Heller, Theodore W. Randolph, and John F. Carpenter: A Discussion of Limitation on the Use of Polymers for Stabilization of Proteins During the Freezing Portion of Lyophilization
- 6: Ken-ichi Izutsu, Sumie Yoshioka, and Shigeo Kojima: Phase Separation and Crystallization of Components in Frozen Solutions: Effect of Molecular Compatibility Between Solutes
- 7: Jennifer L. West: In Situ Formation of Polymer Matrices for Localized Drug Delivery
- 8: Mark R. Prausnitz: Transdermal Delivery of Macromolecules: Recent Advances by Modification of Skin's Barrier Properties
- 9: S. Brocchini, D. M. Schachter, and J. Kohn: Amino Acid Derived Polymers for Use in Controlled Delivery Systems of Peptides
- 10: Gay-May Wu, David Hummel, and Alan Herman: Analysis of the Solution Behavior of Protein Pharmaceuticals by Laser Light Scattering Photometry
- 11: Henryk Mach, Gautam Sanyal, David B. Volkin, and C. Russell Middaugh: Applications of Ultraviolet Absorption Spectroscopy to the Analysis of Biopharmaceuticals
- 12: LaToya S. Jones, Narendra B. Bam, and Theodore W. Randolph: Surfactant-Stabilized Protein Formulations: A Review of Protein Surfactant Interactions and Novel Analytical Methodologies.
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