Radical-mediated protein oxidation : from chemistry to medicine

Bibliographic Information

Radical-mediated protein oxidation : from chemistry to medicine

Michael J. Davies and Roger T. Dean

(Oxford science publications)

Oxford University Press, 1997

  • : hbk.

Available at  / 10 libraries

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Includes bibliographical references and index

Description and Table of Contents

Description

Protein oxidation by free radicals is thought to play a major role in many oxidative processes within cells, and is implicated in human disease, carcinogenesis, and ageing. This unique and comprehensive volume brings together up-to-date information on the oxidation of amino acids, peptides, and proteins by free radicals and discusses the roles of such processes in biological systems. Topics include: the chemistry of amino acid and protein oxidation; the biochemical consequences of these reactions; the role of protein oxidation in normal physiology; the potential importance of protein oxidation in human health - including ageing, heart disease, cancer, inflammation and neurodegenerative diseases - and the possible prevention of such processes by antioxidants and other protective strategies.

Table of Contents

  • A historical survey of the study of radical-mediated protein oxidation
  • Formation and chemistry of radicals involved in amino acid, peptide, and protein oxidation
  • The biochemistry of protein oxidation in cells and cell-free systems
  • The physiology of protein oxidation
  • Pathology of protein oxidation
  • Future directions in the study of protein oxidation
  • References
  • Index

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