Myeloma : biology and management
Author(s)
Bibliographic Information
Myeloma : biology and management
（Oxford medical publications）
Oxford University Press, 1998
2nd ed
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Note
Includes bibliographical references and index
Description and Table of Contents
Description
Myeloma is a malignant disease of the bone marrow, that provides an important role model for many other types of cancer. Although the subject of considerable research, the origins of the disease remain unclear. There has however been an explosion of interest in this disease in the past decade. The 1st edition of Myeloma: Biology and management provided the first authoritative, comprehensive textbook, covering the epidemiology, immunology, and haematology of this important cancer. Since publication in 1995, several important advances have taken place in myeloma research, necessitating a review of the previous text. While bringing fully up to date the topics covered in the 1st edition, the 2nd edition includes several new chapters; the patient and family perspective of the disease, infections in myeloma, cytogenetics, neurological complications, along with a history of myeloma. The book has been written and produced by the leading world-wide authorities in myeloma research. This book is intended for oncologists, heamatologists.
Table of Contents
Part 1 - Pathophysiology. Immunoglobulins. Antibody-secreting cells and their origins. Molecular biology of multiple myeloma. Cytokines and cytokine receptors in human multiple myeloma. Bone marrow biopsy and aspiration for diagnosis of multiple myeloma. The role of cytogenetics in myeloma. Multiple myeloma: A brief history. Part 2 - Clinical features. Epidemiology of myeloma. Clinical presentation and diagnosis. Laboratory investigation of myeloma. Radiology features of myeloma. [Prognostic factor in multiple myeloma - might be deleted]. Part 3 - Therapy of myeloma. Chemotherapy of myeloma. Radiotherapy of myeloma. Haematopoitic stem cell transplantation in multiple myeloma. Management of haematologic complications of myeloma. Disorders of calcium and skeletal metabolism. Management of renal complications. Neurological manifestations of myeloma and their management. Infections in myeloma. Psychosocial aspects of multiple myeloma. Myeloma: Patient and family perspectives. Part 4 - Other disorders associated with paraproteinaemia. Monoclonal gammopathies of undetermined significance. Amyloidosis. Heavy-chain diseases. Waldenstrom's macroglobulinaemia
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