Leukocyte integrins in the immune system and malignant disease
著者
書誌事項
Leukocyte integrins in the immune system and malignant disease
(Current topics in microbiology and immunology, 231)
Springer-Verlag, c1998
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This is an examination of leukocyte integrins in the immune system and malignant disease. Issues addressed include: VLA-4 mediated signalling; the role of alpha4-integrins in T lymphocyte migration into the inflamed and noninflamed central nervous system; and alpha4-integrins and tumour metastasis.
目次
- VLA-4 mediated signalling
- functions of alpha4-beta7-integrins in haematopoiesis, lymphocyte trafficking and organ development
- regulation of integrin function by inside-out signalling mechanisms
- the role of alpha4-integrins in T lymphocyte migration into the inflamed and noninflamed central nervous system
- the roles of alpha4-integrins in the development of insulin-dependent diabetes mellitus
- immunosuppression by blocking alpha4-integrins/VCAM-1 adhesion
- virus-induced T cell aviation and the inflammatory response
- alpha4-integrins and tumour metastasis.
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