Colposcopy in diagnosis and treatment of preneoplastic lesions

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書誌事項

Colposcopy in diagnosis and treatment of preneoplastic lesions

H.-E. Stegner, M. Coppleson (eds.)

Springer-Verlag, c1988

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  • gw

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注記

"Reports from the First International Tutorial on Colposcopy and Colposcope-directed Treatment Procedures, Hamburg, FRG, September 21st and 22nd, 1985"--T.p. verso

Includes bibliographies

内容説明・目次

内容説明

There are few cancers that have been as intensively studied from the epidemiological and morphological aspects as carcinoma ofthe uterine cervix. Current data suggest that sexually transmitted viral infections may playa major role in the pathogenesis of squamous neoplasias of the cervix and the lower genital tract. The risk of developing squamous- cell cancer of the cervix is significantly greater in patients who have been infected by human papillomavirus than in noninfected women. Although infectious dysplasia regresses spontaneously in many cases, it may be an initial step in the natural history of squamous cancer. With the increasing number of young women, often below the age of 20 years with uni-or multicentric dysplastic (intraepithelial neoplas- tic) lesions, diagnostic and therapeutic methods more conservative than traditional conization are needed. The renaissance of colposcopy has fostered a more distinctive look at the spectrum of premalignant lesions and permitted a much more conservative approach to their management. Electrodiathermy, cryosurgery, and more recently carbon-dioxide laser have proven to be appropriate tools with which to destroy the atypical epithelia without mutilating the organs affected. The most important single factor involved in the success of these techniques is meticulous pretreatment assessment of the patient based on skilful colposcopic examination to determine the full extent of any lesion. This can only be done by a physician thoroughly experienced in col- po scopic diagnosis and with a complete understanding of the histoge- nesis of intraepithelial neoplasia.

目次

Cervical Carcinoma - A Continuing Model of Cancer Development.- High-Risk Groups for Cervical Cancer.- Cervical Cancer - An Infectious Disease?.- Involvement of Papillomavirus in Cervical Cancer and Its Precursors.- Malignant and Premalignant Lesions of the Cervix.- Clinical Aspects of Human Papillomavirus (HPV) Infection.- Colposcopic Basis of Histologic Correlation.- The New Nomenclature.- Colposcopy of Hormonally Induced Changes of the Cervix.- Functional Colposcopy.- Colposcopic Differential Diagnosis of Premalignant Lesions of the Cervix.- Pitfalls in Colposcopic Diagnosis.- Correlation of Colposcopic, Cytologic, and Histological Findings in Cases of Cervical Intraepithelial Neoplasia (CIN) and Invasive Cervical Carcinoma and the Importance of Colposcopy in Cancer Control.- Cervicographic Screening.- Therapy of Cervical Intraepithelial Neoplasia.- Destructive Methods in the Treatment of Cervical and Vulval Intraepithelial Neoplasias.- The Efficacy of Electrocoagulation Diathermy in Eradicating Precancerous Lesions of the Cervix.- Management of Refractory Condylomata.- Vaginal Colposcopy.- Preneoplastic Lesions of the Vulva.- Minimal Invasive Cancer of the Cervix: Morphologic Definitions and Clinical Consequences.- On the Problem of the Microinvasive Carcinoma of the Vulva.

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