The endocrinology of bone
著者
書誌事項
The endocrinology of bone
Society for Endocrinology, 1997
大学図書館所蔵 全2件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Proceedings of a symposium held at University College London Medical School
Reprinted from the Journal of Endocrinology, v.154, suppl., September 1997 -- T.p. verso
Includes bibliographical references
内容説明・目次
内容説明
Specialists examine the science and medicine of bone endocrinology in this book. The interest in the use of parathyroid hormone (PTH) as a therapy for osteoporosis, and the issue of the role of polymorphisms in the vitamin D receptor in the genetic element of osteoporosis is discussed. The nature and functions of PTH receptors are also debated, as are the functions and significance in the renal and skeletal systems of the newly-cloned PTH receptor. The clinical management of hypercalcaemic syndromes is also covered. A section of the book covers parathyroid hormone-related peptide (PTD-RP). PTH-RP was first described in humoral hypercalcaemia of malignancy, and also has a role in the normal development of the skeleton. The book asks the question: is it a hormone or a cytokine? The vitamin D axis is also analyzed and reviewed with regard to the molecular basis of its actions and its interactions with the retinoid receptors in normal and disease states, such as vitamin D-resistant rickets. The basis for inherited vitamin D pseudo-deficiency or Prader rickets in children is also described.
The fundamentals of bone biology are examined with respect to the biology of osteoclasts and the role of integrins. The latter have potential as targets for therapies in bone disease, including osteporosis.
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