Base excision repair of DNA damage
Author(s)
Bibliographic Information
Base excision repair of DNA damage
（Molecular biology intelligence unit）
Landes Bioscience, 1997
- International
Available at / 7 libraries
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Digital Library of Nara Institute of Science and Technology
International464.1||MOL||1480023454
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Note
Includes bibliographical references and index
Description and Table of Contents
Description
The text reviews current data on all the different biochemical steps that comprise base excision repair (BER), the primary pathway for removal of alkylation, hydrolytic and oxidative damage to DNA. It covers various aspects from excision of damaged or mismatched bases and repair of baseless sites, through a discussion of the DNA polymerases needed for BER, and eventually to the enzymes that complete the BER process. Where appropriate, the cytotoxic and mutagenic consequences of a failure to complete any particular step in the process are outlined.
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