RNA structure and function
Author(s)
Bibliographic Information
RNA structure and function
(Cold Spring Harbor monograph series, 35)
Cold Spring Harbor Laboratory Press, c1998
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Note
Includes bibliographic references and index
Description and Table of Contents
Description
The striking functional versatility of RNA is attributable to its remarkable capacity for conformational change. Current models of RNA synthesis, its maturation, translation and degradation are all based on specific structures and there is growing appreciation of the functional importance of interactions between RNA and RNA-binding proteins. This work identifies the major intellectual and technical advances in understanding the part played by structure in how RNA works. It encompasses the experimental approaches used to define RNA structure and its influence on RNA functions such as transcription termination, catalysis, recoding and translational control. Investigators with these interests and students of molecular biology should find this volume a provocative survey of a rapidly-advancing field and a valuable complement to the monograph, "The RNA World".
Table of Contents
- From DNA melting profiles to tRNA crystals and RNA chaperones - how the secondary and tertiary structures of ribonucleic acids were discovered - a personal recollection, J.R. Fresco
- modelling the tertiary structure of RNA, R. Cedergren and F. Major
- probing RNA structure and function in solution, H. Moine et al
- nuclear magnetic resonance spectroscopy of RNA, E.V. Puglisi and J.D. Puglisi
- cyrstallographic analysis of RNA structure, S.R. Holbrook
- inferring RNA structure by phylogenetic and genetic analyses, F. Michel and M. Costa
- directed evolutionary descriptions of natural RNA structures, S. Baskerville et al
- ribosomal RNA, H.F. Noller
- RNA-RNA interactions in nuclear pre-mRNA splicing, T.W. Nilsen
- structure and catalytic function of the bacterial ribonuclease P ribozyme, M.E. Harris et al
- small ribozymes, S.T. Sigurdsson et al
- RNA mimicry in the translations apparatus, M. Springer et al
- pseudoknots, RNA folding and translational regulation, D.E. Draper et al
- antisense RNA structure and function, B.N. Zeiler and R.W. Simons
- tRNA/aminoacyl-tRNA synthetase interactions, J.G. Arnez and D. Moras
- translational control by mRNA structure in eubacteria - molecular biology and physical chemistry, M.H. de Smit
- RNA structure in transcription elongation, termination and antitermination, T. Platt
- RNA structure and function in cellular iron homeostasis, J.B. Harford and T.A. Rouault
- RNA structures involved in selenoprotein synthesis, A. Huttenhofer and A. Bock
- role of RNA structure in RNA editing, G.J. Connell and L. Simpson
- telomerase RNA structure and function, E.H. Blackburn
- RNA ligases - function, mechanism and sequence conservation, E.A. Arn and J. Abelson.
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