Correcting the blueprint of life : an historical account of the discovery of DNA repair mechanisms

Bibliographic Information

Correcting the blueprint of life : an historical account of the discovery of DNA repair mechanisms

Errol C. Friedberg

Cold Spring Harbor Laboratory Press, 1997

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Note

Includes bibliographical references (p. 191-201) and index

Description and Table of Contents

Description

In this brief, readable, and revealing book, one of the pioneers of the now rapidly evolving field of DNA repair traces the history of the discovery of the more important mechanisms by which cells respond to DNA damage. Errol Friedberg has written an enjoyable and informative introduction to the study of DNA mutagenesis and re-pair that will interest students at an advanced undergraduate or graduate student level as well as investigators in fields as diverse as oncogenesis, cell cycle regulation, transcription and DNA replication.

Table of Contents

  • In the beginning
  • let there be light - the discovery of enzymatic photoreactivation
  • the emergence of excision repair
  • new mechanisms for repairing DNA
  • mismatched bases are repaired by yet a different mode
  • the remarkable SOS phenomenon
  • epilogue - molecule of the year 1994.

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