Architect of intermediary metabolism, 1933-1937/ Frederic Lawrence Holmes
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Bibliographic Information
Architect of intermediary metabolism, 1933-1937/ Frederic Lawrence Holmes
（Monographs on the history and philosophy of biology, . Hans Krebs / Frederic Lawrence Holmes ; v. 2）
Oxford University Press, 1993
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Note
Includes bibliographical references and index
Description and Table of Contents
Description
This comprehensive volume completes Frederic Holmes's notable and detailed biography of Hans Krebs, from the investigator's early development through the major phase of his groundbreaking investigation, which lay the foundations upon which the modern structure of intermediary metabolism is built. With access to Krebs's research notebooks as well as to Krebs himself through more than five years of personal interviews, the author provides an insightful analysis of
Hans Krebs and of the scientific process as a whole. The first volume, published in 1991, covered Krebs's formative years in Germany, his work with Otto Warburg, and his discovery of the urea cycle in 1932. This second volume reconstructs the investigative pathway and the professional and personal
life of Hans Krebs, from the time of his arrival in England in 1933 until 1937, when he made the discovery for which he is best known-the formulation of the citric acid cycle. Holmes portrays Krebs's activity at the intimate level of daily interactions of thought and action, from which the characteristic patterns of scientific creativity can best be seen. Holmes's fascinating portrait of Krebs integrates the great scientist's investigative pathways with his personal life. The result is an
illuminating analysis of both man and scientist that will be of interest to biochemists and historians of science.
Table of Contents
- Introduction
- 1. A new home for a career
- 2. Laboratory life in Cambridge
- 3. Progress under pressure
- 4. New moves
- 5. Arrivals and partings
- 6. The "Great Work"
- 7. Relocations and dismutations
- 8. Main routes and carriers
- 9. Full circle
- 10. Reflections
- Guide to structural formulas
- Notes
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