Cytokines in veterinary medicine
著者
書誌事項
Cytokines in veterinary medicine
CAB International, c1997
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注記
Includes bibliographical references (p. 311-318) and index
内容説明・目次
内容説明
Cytokines are regulatory proteins that act as intercellular communication signals in a variety of processes, including embryonic development, haematopoiesis, stress, inflammation, immunity and tissue repair. Studies since the early 1980s have established the vital role of cytokines in humans and rodent models for the immune, endocrine and neuronal systems. More recently, attention has turned to the cytokines of animals of veterinary importance. This book addresses basic research on cytokines and its clinical potential for veterinary medicine. Cytokines in cattle, sheep, pigs, horses, cats, dogs and birds are considered. It is shown how recent knowledge has exploded, particularly through the use of recombinant DNA and PCR technologies. The role of cytokines in the pathogenesis, diagnosis and therapy of animal diseases is reviewed, as is the utility of animal models to investigate diseases analogous to those in humans. It is shown how measurements of cytokines might be used as immunological monitors of disease progression and prognosis, how their administration to production animals might improve health status and how they might be used as vaccine adjuvants or as adjuncts to chemotherapy. Written by leading authorities from Europe, North America, Africa and Australia, the book is essential for research workers in veterinary microbiology and immunology, as well as medical scientists interested in applying this work to human health.
目次
Part I: Bovine Cytokines, edited by L A Babiuk 1: Applications of Bovine Cytokines D L Godson, M E Baca Estrada and L A Babiuk 2: Type 1 and Type 2 Responses in Cattle and their Regulation W C Brown and D M Estes 3: The IFN-g Assay as a Diagnostic Test for Bovine Tuberculosis P R Wood and J S Rothel 4: Interferons in Pregnancy of Domestic Animals A P F Flint 5: Immunotherapy of Bovine Ocular Squamous Cell Carcinoma and Bovine Vulval Papilloma and Carcinoma with IL-2 V Rutten 6: Cytokines and Bovine Herpesvirus 1 E Hanon, C Hamers and P P Pastoret Part II: Ovine Cytokines, edited by C J McInnes 7: A Current Perspective of Ovine Cytokine Research C J McInnes, E A Innes, J Brown and G Entrican 8: Recombinant Ovine Interleukin-1b as an Adjuvant for Multivalent Bacterial Vaccines M Elhay, G Barcham, A Cameron, A Andrews and A Nash Part III: Porcine Cytokines, edited by F Blecha 9: Cytokine Applications in Pigs F Blecha 10: Recent Progress in the Molecular Characterization of Porcine Cytokines K Vandenbroeck and A Billiau Part IV: Equine Cytokines, edited by D W Horohov 11: Cytokine Production in Equine Disease D W Horohov, C E Swiderski, J A Robinson and T R Klei 12: The Cloning of Equine Type I and Type II Interferons A Himmler and G Grunig 13: Cytokines in the Pathogenesis of Equine Joint Disease S A May Part V: Canine Cytokines, edited by E Pinelli 14: Cytokines in Canine Visceral Leishmaniasis E Pinelli 15: The Role of Canine IFN-g in Graft Rejection Evaluated in the Canine Transplant Model L Fuller, K Zucker, D Asthana, S Zhen, M Carreno, V Esquenazi and J Miller 16: Cytokines in Canine Septic Shock A G Coran and R A Drongowski Part VI: Feline Cytokines, edited by V E C J Schijns 17: Feline Cytokines V E C J Schijns and W G Bradley 18: Cytokine Expression During Feline Immunodeficiency Virus Infection W G Bradley 19: Cytokines in Feline Infectious Peritonitis V E C J Schijns, B L Haagmans and M C Horzinek Part VII: Avian Cytokines, edited by K A Schat 20: Avian Cytokines K A Schat and P Kaiser 21: Lymphocyte Transformation and Lymphokine Production During Chicken Anaemia Virus Infection B M Adair and M S McNulty 22: Index
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