Discontinuous conduction in the heart

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Bibliographic Information

Discontinuous conduction in the heart

edited by Peter M. Spooner, Ronald W. Joyner, José Jalife

(American Heart Association monograph series)

Futura, c1997

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Note

Summaries of presentations from a 1995 research workshop sponsored by the Basic Science Council of the American Heart Association and the National Heart, Lung, and Blood Institute in Hilton Head, S.C

Includes bibliographical references and index

Description and Table of Contents

Description

Discontinuity in cardiac construction, multidimensional divergence and

Table of Contents

  • Preface
  • Section I: Normal Cardiac Conduction: Introduction
  • 1. Discontinuous Cardiac Conduction: Its Origin in Cellular Connectivity With Long-Term Adaptive Changes That Cause Arrhythmias
  • 2. Gap Junction Channels and Cardiac Conduction
  • 3. Nonjunctional Channels of Cardiac Cells and Metabolic Oscillations as Contributors to Discontinuous Conduction
  • Section II: Discontinuous Conduction and Arrhythmias: Introduction: 4. Gap Junction Structure, Conduction, and Arrhythmogenesis: Directions for Future Research
  • 5. Role of Discontinuous Electrical Propagation in Clinical Atrial Arrhythmias: Current Evidence and Future Directions
  • 6. Role of Discontinuous Conduction/Nonuniform Anisotropy in Clinical Arrhythmias
  • Section III: Gating and Modulation of Gap Junctions: Introduction: 7. Structure of Cardiac Gap Junction Membrane Channels: Progress Toward a Higher-Resolution Model
  • 8. Major Cell Biological Issues and Strategies in Discontinuous Conduction
  • 9. Molecular Analysis of the pH Regulation of the Cardiac Gap Junction Protein Connexin43
  • 10. Triggered Propagated Contractions and Arrhythmias Caused by Acute Damage to Cardiac Muscle
  • 11. Microscopic Conduction in Cell Cultures Assessed by High-Resolution Optical Mapping and Computer Simulation
  • Section IV: Waves and Arrhythmias: Introduction: 12. Scale of Geometric Structures Responsible for Discontinuous Propagation in Myocardial Tissue
  • 13. Wave-Front Curvature Leads to Slow Conduction and Block in Two-Dimensional Cardiac Muscle
  • 14. Antiarrhythmic and Proarrhythmic Mechanisms in Cardiac Tissue: Linking Spiral Waves, Reentrant Arrhythmias, and Electrocardiographic Patterns
  • Section V: Junctional Channels and Molecular Genetics: Introduction: 15. Molecular and Biochemical Regulation of Connexins: Potential Targets for Modulation of Cardiac Intercellular Communication
  • 16. Can We Learn About Conduction by Use of Genetic Approaches? Section VI: Discontinuous Conduction in Myocardial Ischemia: Introduction: 17. Characteristics and Causes of Conduction Changes Associated With 1a and 1b Arrhythmias in Acute Ischemia
  • 18. Discontinuous Conduction in the Epicardial Border Zone of Infarcted Hearts and Its Role in Anisotropic Reentry
  • 19. Is There a Pharmacology for Discontinuous Conduction? Section VII: Contemporary Model Studies of Discontinuous Conduction: Introduction: 20. Discontinous Conduction in the AV Junctional Area
  • 21. Experimental Simulations of Variations in Junctional Conductance
  • 22. Membrane Factors and Gap Junction Factors as Determinants of Ventricular Conduction and Reentry
  • Perspectives and Future Directions: Arrhythmias and Discontinuous Conduction
  • Index

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