書誌事項

Pulmonary edema

edited by E. Kenneth Weir and John T. Reeves

(American Heart Association monograph series)

Futura, c1998

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Here is a clear, well organized, and expertly detailed review of the current knowledge regarding the genesis and clearance of lung fluid at rest and during exercise, in neonates and adults. This book explains, at both the molecular and cellular level, the mechanisms underlying the pathophysiology of varying pulmonary oedemas. Based on this understanding, new treatment approaches are explored. Beginning with comparative physiology and a variety of animal models including the newborn, the authors go on to discuss: liquid flow within the lung and its reabsorption from the alveoli the activity within microvascular endothelial cells hydrostatic pressure effects the problem of increased leakiness of the alveolar-capillary barrier possible interactions with particular barrier molecules

目次

ForewordN.C. Staub, Sr. Section I. The Physiology of Lung Fluid Balance 1. Fluid Balance in Vertebrate Lungs: Are All Lungs "Dry"?A.W. Smits 2. Structure-Function Relationships in the Pathogenesis of Pulmonary EdemaH. Bachofen, E.R. Weibel 3. Pressure, Flow, and Filtration in the Lung During Strenuous ExerciseJ.H. Newman, C.I. Hermo 4. Lung Edema in NeonatesC.D. Fike 5. Aquaporins, Caveolae, and Capillary PermeabilityJ.E. Schnitzer 6. Mechanisms of Edema ClearanceY. Berthiaume 7. Role of Active Sodium Transport in Reabsorption of Pulmonary EdemaR.L. Lubman, E.D. Crandall 8. Surfactant - Edema InteractionsA.H. Jobe Section II. Filtration Pressures And Pulmonary Edema 9. Interstitial Mechanics and Fluid FlowS.J. Lai-Fook 10. The Interstitial and Microvascular Unit of the Lung: From the Neonate to the AdultG. Miserocchi 11. Strength, Failure, and Remodeling of the Pulmonary Blood-Gas BarrierJ.B. West, E.C. Breen, O. Mathieu-Costello 12. Effect of the Distribution of Vascular Pressures on Pulmonary EdemaJ.U. Raj 13. Effects of Sustained Hydrostatic Pressure on the Expression of Endothelial Cell-Leukocyte Adhesion MoleculesE.A. Schwartz, R. Bizios, M.E. Gerritsen Section III. Increased Permeability And Pulmonary Edema 14. Mechanisms of Receptor-Initiated Changes in Endothelial PermeabilityD.M. Shasby, A.B. Moy 15. Regulation of Alveolar Capillary Barrier Function by NeutrophilsC.D. Doerschuk, H. Kubo, H. Motosugi, N.A. Doyle, W.M. Quinlan, G.J. Kutkoski 16. Mechanisms of Ischemia-Reperfusion Injury in the LungT.M. Moore, P.L. Khimenko, A.E. Taylor 17. Endothelial Cell Activation and Barrier DysfunctionH. Lum 18. Regulation of Myosin Phosphorylation and Barrier Function in EndotheliumJ.G.N. Garcia, L.I. Gilbert-McClain 19. The Counteradhesive Proteins, SPARC and Thrombospondin-1, Regulate Endothelial Barrier Function Through Protein Tyrosine PhosphorylationS.E. Goldblum 20. Oxidants and Endotoxin-Induced Endothelial InjuryB. Meyrick 21. Effects of Extracellular Nucleotides on Lung Vascular Endothelial CellsS. Rounds, D.D. Dawicki, A.L. Parker, L.L. Likar 22. Promotion of Regeneration and Repair After Acute Lung InjuryP.B. Bitterman, V. Polunovsky 23. Is There A Genetic Susceptibility Which May Predispose to the Development of the Acute Respiratory Distress Syndrome (ARDS)?N.F. Voelkel, J. Allard, S. Abman Section IV. Treatment Of Pulmonary Edema 24. Treatment of the Adult Respiratory Distress Syndrome: A Pathophysiological ApproachR.J. Mangialardi, G.R. Bernard 25. Acute and Chronic Efficacy of Nitric Oxide in the Adult Respiratory Distress Syndrome (ARDS)R. Rossaint, K. Falke 26. Pulmonary Vascular Coronary Mechanisms in Sepsis and Acute Lung InjuryN.P. Curzen, T.W. Evans

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