Strategies for organic drug synthesis and design
著者
書誌事項
Strategies for organic drug synthesis and design
(A Wiley-Interscience publication)
J. Wiley, c1998
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注記
Includes index
内容説明・目次
内容説明
All of the breadth and depth of organic drug synthesis-in one resource This work offers a clear examination of the synthetic routes followed to prepare a range of compounds with assigned generic names. With drugs selected for the illustrative value of the chemistry used for synthesis, the book illustrates a great variety of organic transformations and structural classes of compounds. Ideal for anyone learning or working in organic, medicinal, or pharmaceutical chemistry today, Strategies for Organic Drug Synthesis and Design includes: Coverage of carbocyclic and heterocyclic compounds-steroids, opioid analgesics, beta lactam antibiotics, and more Hundreds of reaction flow charts detailing routes used to prepare over 600 compounds Biological rationales for drug classes and actions of individual agents Capsule presentations of basic principles of drug action An extensive chemical reaction index with over 3,000 entries.
目次
- Prostaglandins, Protease Inhibitors, and Retinoids.
- Drugs Based on a Substituted Benzene Ring.
- Indenes, Naphthalenes, and Other Polycyclic Aromatic Compounds.
- Steroids: Part 1: Estranes, Gonanes, and Androstanes.
- Steroids: Part 2: Compounds Related to Progesterone and Cortisone.
- Nonsteroidal Estrogens and Their Antagonists.
- Opioid Analgesics.
- Drugs Based on Five--Membered Heterocycles.
- Drugs Based on Six--Membered Heterocycles.
- Five--Membered Heterocycles Fused to a Benzene Ring.
- Six--Membered Heterocycles Fused to a Benzene Ring.
- Seven--Membered Heterocyclic Rings Fused to Benzene.
- Heterocycles Fused to Two Benzene Rings.
- Beta--Lactam Antibiotics.
- Heterocycles Fused to Other Heterocyclic Rings.
- Cross Index of Compounds.
- Indexes.
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