Dermal absorption and toxicity assessment
著者
書誌事項
Dermal absorption and toxicity assessment
(Drugs and the pharmaceutical sciences, v. 91)
Marcel Dekker, c1998
大学図書館所蔵 全8件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
This volume examines the dermal absoption process with emphasis on determining the toxicity arising from exposure to pharmaceuticals, cosmetics, and other substances. It serves as a bench resource for scientists seeking effective and timesaving means of estimating risk. Contributors also reveal how environmental hazards such as metal compounds, contaminated soil and water, and sun sensitivity occur and are measured through the skin. Practical information is provided on specific products, from analgesics and anti-inflammatory drugs, to perfumes, sunscreens and hair dyes.
目次
- The relationship between structure and barrier function of skin
- dermal metabolism
- systemic toxicity in man secondary to percutaneous absorption. Part 1 Modelling of dermal risk assessment: occupational skin disease - a case study
- current issues in the in vitro measurement of percutaneous absorption
- investigation of the skin permeation in vitro
- prediction -physiological models
- prediction - simple risk models and overview of dermal risk assessment
- cutaneous microdialysis for human in vivo dermal absorption studies
- physicochemical determinants of stratum corneum permeation. Part 2 Pharmeceuticals: in vitro/in vivo correlations in transdermal drug delivery
- irritancy of topical chemicals and transdermal delivery systems
- chemical penetration enhancement - possibilities and problems
- drugs used for skin diseases
- drugs for pain and inflammation
- site of effects
- iontophoresis
- topical therapeutic agents used in wound care. Part 3 Cosmetics: regulation of cosmetics in the United States
- experimental design considerations and use of in vitro skin penetration data in cosmetic risk assessment
- percutaneous absorption of hair dyes
- sunscreens - toxicological aspects
- exposure to fragrances - their absorption and potential toxicity. Part 4 Environmental: dermal absorption and toxicity assessment
- human skin penetration by metal compounds
- soil contamination -theoretical descriptions
- percutaneous absorption of hazardous substances from soil and water
- bathing water - percutaneous absorption of water contaminants
- ultrastructural effects of some solvents and vehicles on the stratum corneum and other skin components - evidence for an extended mosaic-partitioning model of the skin barrier.
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