Molecular genetics of early human development
著者
書誌事項
Molecular genetics of early human development
（The Human molecular genetics series / series advisors, D.N. Cooper, S.E. Humphries, T. Strachan）
BIOS Scientific, c1997
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内容説明・目次
内容説明
Aimed at all researchers into human development and the wider medical research audience, this text brings together various strands of the discipline of the molecular genetics of early human development, and provides examples of the approaches being used. Human development disorders are a significant clinical burden and should ideally be investigated by the study of normal human embryos. However, the studies have been hampered by the lack of material and by public sensitivities. Much reliance has been placed on extrapolating data from mouse embryos, but there is an increased awareness of fundamental differences between the mouse and human genomes.
目次
- Mouse and human embryonic development - a comparative overview
- why study human embryos
- the imperfect mouse model
- ethics of human embryo studies
- current methods of human embryo collection
- three-dimensional modelling of human embryo morphology
- studying gene expression in human embryos
- biological studies and studying gene expression in pre-implantation human embryos
- expression of HOX and Wnt genes in post-implantation human embryos
- studying expression patterns of genes involved in mental retardation
- three-dimensional atlas of mouse development - a model for a future electronic database of early human development. (Part contents)
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