Ovulation and its disorders : themes from the XIth World Congress on Fertility and Sterility, Dublin, June 1983, held under the auspices of the International Federation of Fertility Societies

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Ovulation and its disorders : themes from the XIth World Congress on Fertility and Sterility, Dublin, June 1983, held under the auspices of the International Federation of Fertility Societies

edited by W. Thompson, R.F. Harrison, and J. Bonnar

(Studies in fertility and sterility)

MTP Press, c1984

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Includes bibliographies and index

Description and Table of Contents

Description

This monograph contains a selection of papers presented at the Xlth World Congress of Fertility and Sterility (Dublin, 1983); the central theme is ovarian function and treatment of its disorders. Cross-cultural research provides international congresses with their unique quality due to the world-wide exchange of views; we think this aim has been achieved and reflected in this book. During the past decade significant advances have been made in our understanding of the events surrounding human ovulation leading to the development of an increasing range of effective therapeutic agents and the more logical use of existing drugs. As a result infertile patients with disordered ovulation can now anticipate a more favourable out- come. In addition more sophisticated diagnostic methods have revealed the presence of minor defects in ovarian function in some patients previously labelled as 'unexplained infertility'. The identification of such problems can only lead to further therapeutic success. The contents of this volume reflect many different aspects of the study of ovulation including the monitoring of both follicular growth and the luteal phase, the role of prolactin and the treatment of ovulatory dysfunction. We are sure that the wide range of topics will evoke continued interest in these subjects. We extend our thanks to the invited speakers for their excellent contributions in lecture and essay form and express our gratitude for the unfailing help we received from the staff of MTP Press in the preparation of this volume.

Table of Contents

Section 1: Monitoring Ovulation.- 1 Ultrasonic and endocrinologic monitoring of follicular growth during spontaneous and clomiphene stimulated cycles.- 2 The use of ultrasonography to detect ovulation.- 3 Ultrasound versus laparoscopy in the diagnosis of the LUF syndrome.- 4 Radioimmunoassay of progesterone in human saliva.- 5 Serum progesterone levels as a criterion of ovulation.- 6 How unexplained is the unexplained cause of infertility?.- 7 Opioid peptides effects on female fertility.- Section 2: The Evaluation of Corpus Luteum Function.- 8 Concentration of prostaglandin F in human peripheral venous plasma and in corpus luteum.- 9 Estimation of corpus luteum function using follicular phase plasma progesterone concentration.- 10 Analysis of luteal insufficiency in infertile women.- 11 Causes of plasma progesterone concentrations above the 'normal' range in the preovulatory phase.- 12 Premenstrual progesterone levels in menstrual cycles with short luteal phases.- 13 The trapped ovum - biochemical, ultrasonic and laparoscopic findings.- 14 Hormonal concentrations of serum and peritoneal fluid of women with unexplained infertility (LUF syndrome).- 15 Origin of low peritoneal fluid steroid concentrations in the luteinized unruptured follicle syndrome.- Section 3: Prolactin Secretion.- 16 Stimulation of prolactin secretion by Cimetidine, a histamine H2-receptor antagonist, in women.- 17 Effect of a dopamine agonist and metoclopramide on gonadotrophin release.- 18 Prolactin and receptor capacity of the human corpus luteum.- 19 Discrepancy of endometrial dating in the mid-luteal phase of hyperprolactinaemic women.- 20 Methergoline therapy of amenorrhoea and sterility in women with normal prolactin secretion.- 21 Long-term follow up of the female hyperprolactinaemic syndrome treated with bromocriptine.- 22 Metergoline and bromocriptine in the management of tumoural and idiopathic hyperprolactinaemia.- 23 Clomiphene citrate and bromocriptine versus placebo in the treatment of idiopathic infertile couples.- Section 4: Treatment of Ovulatory Dysfunction.- 24 Induction of ovulation in hypothalamic amenorrhoea with gonadotrophin releasing hormone.- 25 Induction of ovulation with purified urinary FSH in patients affected by PCOS.- 26 Induction of ovulation with the anti-oestrogen Tamoxifen.- 27 Prednisolone-clomiphene treatment in patients who fail to respond to clomiphene - role of prednisolone.- 28 Serum oestradiol values after extended clomiphene citrate therapy.- 29 Sex ratio of infants born following induction of ovulation.- 30 Monitoring ovulation induction with hMG/hCG by oestrogen determination and ultrasonography.- 31 A comparison of two methods for monitoring gonadotrophin therapy.- 32 Repetitivity and therapy of luteinized unruptured follicle syndrome.- 33 Antibiotic therapy for luteal phase defect and premenstrual syndrome.

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