CNS injuries : cellular responses and pharmacological strategies

Bibliographic Information

CNS injuries : cellular responses and pharmacological strategies

edited by Martin Berry, Ann Logan

(Pharmacology & toxicology)

CRC Press, c1999

Other Title

Central nervous system injuries

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

The basic science of the cellular and molecular responses of the brain to injury is a rapidly expanding area of research that provides evidence of growing opportunities for pharmacological intervention in the clinic. CNS Injuries: Cellular Responses and Pharmacological Strategies is an up-to-date examination of new developments in our understanding of the cellular and trophic responses to CNS injuries and the potential treatment. This text collates reviews of the most important areas of study regarding injury response including inflammatory and immune reactions scarring neuron death demyelination and remyelination axonal regeneration re-establishment of neuronal connectivity Providing a record of recent advances that will help point the way to future developments, this enlightening reference is sure to benefit researchers and practitioners in a broad range of disciplines, including: neurology, pharmacology, pathology, toxicology, immunology, and many others.

Table of Contents

Cellular Responses to Penetrating CNS Injury, M. Berry, A. Butt, and A. Logan Cellular Responses to Ischaemic CNS Injury, W.L. Maxwell The Immune Response and CNS Injury, N.A. Gregson Haematogenous Cell Responses to CNS Injury, K.A. Brown and B.A. Khoshkbijari Role of Macrophages and Microglia in the Injured CNS, W.J. Streit Cellular Trafficking, A.J. Vora and K.A. Brown Protease Inhibitors and Microglia/Macrophage-Modulating Drugs Prevent Microglia-Mediated Neuronal Death in the Traumatised and Dystrophic Retina, S. Thanos, R. Naskar, and P. Heiduschka Transforming Growth Factor-b and CNS Scarring, A. Logan and M. Berry Neurotrophic Factors, T. Hagg Fibroblast Growth Factors, C. Grothe, C. Meisinger, and K. Wewetzer Index Audience

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