Eosinophils in allergy and related diseases : proceedings of a workshop, Tokyo, Japan, June 28, 1997
著者
書誌事項
Eosinophils in allergy and related diseases : proceedings of a workshop, Tokyo, Japan, June 28, 1997
（International archives of allergy and immunology, v. 117 ; Supplement ; 1）
S. Karger, 1998
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内容説明・目次
内容説明
Ten years after the 1st Eosinophil Workshop in Allergy and Related Diseases was held in Tokyo, this volume contains articles based on the presentations given during a second workshop held in June of 1997. During the intervening years, many discoveries concerning eosinophils have been made. These include cloning of the genes for eosinophil granule proteins such as MBP and EDN, isolation and characterization of the IL-5 receptor and cloning of its gene identification of cytokines generated and released by human eosinophils, understanding of the role of adhesion molecules in eosinophil recruitment and activation, and development of a new method for eosinophil purification. The Workshop, now held annually in Tokyo, has reflected these trends in research. The articles in the volume show how current research is aimed at elucidating the eosinophil activation process at a molecular level and identifying the molecules on the surface of and/or within the eosinophil and T cells regulating eosinophil recruitment and activation.
目次
- The involvement of CD80 and CD86 constimulatory molecules in the induction of eosinophilia in mice infected with Nipponstrongylus brasiliensis
- identification of cDNA for rat homologues of human major basic protein and eosinophil cationic protein
- modulation of normal human eosinophil chemotaxis in vitro by herbimycin A, erbstatin and pervanadate
- blockade of CD28/B7 interaction suppresses allergic eosinophilic inflammation in mice
- effect of immunotherapy on the production of eosinophil adhesion-inducing activity from mononuclear cells in house-dust-mite-sensitive bronchial asthma
- IL-5-producing T cells that induce airway eosinophilia and hyperresponsive are suppressed by dexamethasone and cyclosporin A in mice
- heterogeneous expression of tumour necrosis factor-alpha receptors I and II on human peripheral eosinophils
- altered expression of CD11b and CD62L after cross-liking of CD45 isoforms of human eosinophils
- RANTES augments eosinophil lucigenin-dependent chemiluminescence
- involvment of beta1 and beta2 integrin stimulation in RNA synthesis in an eosinophilic cell line (EoL-1)
- human skin mast cells produce TNF-alpha by substance P
- eosinophil degranulation in the presence of lung fibroblasts
- human eotaxin induces eosinophil-derived neurotoxin release from normal human eosinophils
- suppressive effects of SP-A on ionomycin-induced IL-8 production and release by eosinophils
- signal transduction in activation of human eosinophils - G protein-dependent and -independent pathways
- cross-linking of the beta2 integrin, CD11b/CD18, on human eosinophils induces protein tyrosine phosphorylation and cellular degranulation
- interferon-gamma receptor beta-chain expression and formation of alpha- and beta-chain complexes after receptor conjugation on human peripheral eosinophils
- whole-blood flow-cytometric analysis of eosinophil EG2 expression as a marker of the pathological conditions of asthma.
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