Liquid chromatography-mass spectrometry

書誌事項

Liquid chromatography-mass spectrometry

W.M.A. Niessen

(Chromatographic science series, v. 79)

M. Dekker, c1999

2nd ed., rev. and expanded

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This volume comprehensively relates developments, principles, and applications of combined liquid chromatography-mass spectrometry and other techniques such as capillary electrophoresis and supercritical fluid chromatography combined with mass spectrometry. It covers historical developments, currently important interfaces and technologies, and LC-MS applications in environmental analysis, pharmaceuticals and bioanalysis, and additional fields. It offers in-depth coverage of interfaces and technologies currently important in the laboratory, especially electrospray and APCI, contains an expanded applications section, and provides over 2200 references, tables, equations, and drawings.

目次

GENERAL INTRODUCTION Introduction to Liquid Chromatography Introduction to Mass Spectrometry General Instrumental Considerations in LC-MS Interfacing INTERFACE TECHNOLOGY History of LC-MS Particle-Beam Interface Continuous-Flow Fast-Atom Bombardment Thermospray Interface Nebulization Ionization in LC-MS Electrospray Interfacing Atmospheric-Pressure Chemical Ionization Interfaces Recent Developments in LC-MS Interfacing APPLICATIONS Environmental Applications of LC-MS Pharmaceutical Applications of LC-MS Natural Products and Endogenous Compounds Biochemical Applications of LC-MS Miscellaneous Applications of LC-MS RELATED TECHNIQUES Supercritical Fluid Chromatography Mass Spectrometry Capillary Electrophoresis Mass Spectrometry

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