Affinity biosensors : techniques and protocols

書誌事項

Affinity biosensors : techniques and protocols

edited by Kim R. Rogers and Ashok Mulchandani

(Methods in biotechnology, 7)

Humana Press, c1998

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

The frequency of reports concemmg the interface of biological reco- tion elements to signal transduction technologies has risen dramatically over the last decade. Because any one of a wide variety of biological recognition elements (e. g. , antibodies, receptors, DNA, microorganisms, or enzymes) can theoretically be interfaced with any one of a wide variety of signal transducers (e. g. , optical, electrochemical, thermal, or acoustic), the potential range of devices and techniques can be bewildering. The purpose of this volume and the previous volume in this series is to provide a basic reference and startmg point for investigators in academics, mdustry, and government to begin or expand their biosensors research. This volume, Methods in Biotechnology vol. 7: Affinity Biosensors: Techniques and Protocols, describes a variety of classical and emerging transduction technologies that have been interfaced to bioaffinity elements (e. g. , antibodies and receptors). Some of the reasons for the expansion in the use of affinity-based biosensors include both advances in signal transduction technologies (e. g. , fiber optics, microelectromcs, and microfabrication) and the availability of bioafflmty elements. More specifically, with respect to biological recognttion elements, commercially and noncommercially produced antibodies directed toward a variety of analytes have become widely available. In addition, te- niques for the purification and stabilization of receptors have also significantly improved. As a result of these recent advances in the field, biosensors research and development projects are being pursued by mvestigators from a wide range of disciplines.

目次

Part I.Affinity Biosensors. Principles of Affinity-Based Biosensors, Kim R. Rogers . Immunobiosensors Based on ThermsitorsKumaran Ramanathan, Masoud Khayyami, and Bengt Danielsson. Affinity Biosensing Based on Surface Plasmon Resonance Detection, Bo Liedberg and Knut Johansen. Immunosensors Based on Piezoelectric Crystal Device, Marco Mascini, Maria Minunni, George G. Guibault, and Robert Carter. Immunobiosensors Based on Evanescent Wave Excitation, Randy M. Wadkins and Frances S. Ligler. A Galactose-Specific Affinity Hollow Fiber Sensor Based on Fluorescense Resonance Energy Transfer,Ralph Ballerstadt and Jerome S. Schultz. Fiberoptic Immunosensors with Continuous Analyte Response, J. Rex Astles, W. Greg Miller, C. Michael Hanbury, and F. Philip Anderson. Immunobiosensors Based on Grating Couplers, Ursula Bilitewski, Frank Bier, and Albrecht Brandenberg. Receptor Biosensors Based on Optical Detection, Kim R. Rogers and Mohyee E. Eldefrawi. Part II.Biosensor-Related Techniques. Immunobiosensors Based on Ion-Selective Electrodes, Hanna Radecka and Yoshio Umezawa. Biosensors Based on DNA Intercalation Using Light Polarization, John J. Horvath. ISFET Affinity Sensor, Geert A. J. Besselink and Piet Bergveld. Liposome-Based Immunomigration Assays, Matthew A. Roberts and Richard A. Durst . Isolated Receptor Biosensors Based on Bilayer Lipid Membranes, Masao Sugawara, Ayumi Hirano, and Yoshio Umezawa. Eukaryotic Cell Biosensor: The Cytosensor Microphysiometer, Amira T. Eldefarwi, Cheng J. Cao, Vania I. Cortes, Robert J. Mioduszewski, Darrel E. Menking, and James J. Valdes. Index.

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