Histological typing of tumours of the exocrine pancreas
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書誌事項
Histological typing of tumours of the exocrine pancreas
（International histological classification of tumours）
Springer-Verlag, 1998, c1996
2nd ed, corr. printing
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注記
First edition published by WHO in 1978 in the International histological classification of tumour series
内容説明・目次
内容説明
This is a histological classification of tumours and tumour-like lesions of the exocrine pancreas which also includes those tu- mours showing a mixture of exocrine and endocrine elements. The classification is based principally on standard microscopic observations, but whenever indicated it incorporates diagnosti- cally valuable immunohistological findings. In addition, the most important immunohistological findings which are helpful in cat- egorizing pancreatic tumours are summarised in Table 1. The major guideline of this classification scheme is the group- ing of the pancreatic exocrine tumours according to their biologi- cal behaviour. Thus, the neoplasms are broadly divided into benign (adenoma) and malignant tumours (carcinoma). How- ever, in recent years we have learned that this division is not a sharp but rather a gradual transition. We therefore added a third group which we call "tumours of uncertain malignant potential" representing a borderline category analogous to that recognized for some ovarian tumours. This group includes mucinous cystic tumour, intraductal papillary-mucinous tumour and solid- pseudopapillary tumour.
These neoplasms are defined by the grade of dysplasia and/or potential to become malignant. Mucinous cystic tumours of uncertain malignant potential, for instance, exhibit moderate epithelial dysplasia, but do not show severe dysplasia/carcinoma in situ changes, nor carcinomatous invasion of the cyst wall or the adjacent pancreatic tissue. Solid- pseudopapillary tumour has a benign looking histological ap- pearance, but metastases may occur. Biologically, all these neoplasms are primarily slow-growing lesions and have an excel- lent prognosis when adequately treated by complete resection.
目次
Histological Classification of Tumours of the Exocrine Pancreas.- Definitions and Explanatory Notes.- Epithelial Tumours.- Nonepithelial Tumours.- Secondary Tumours.- Tumour-like Lesions.- Illustrations.
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