The development of human gene therapy

Bibliographic Information

The development of human gene therapy

edited by Theodore Friedmann

(Cold Spring Harbor monograph series, 36)

Cold Spring Harbor Laboratory, c1999

Available at  / 24 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

This text chronicles the evolution of human gene therapy, illustrating how imaginative concepts shaped the development of technologies. It should be of interest to those interested in clinical medicine, biotechnology and the biology of gene transfer.

Table of Contents

  • The origins, evolution and directions of human gene therapy
  • retroviral vectors
  • lentiviral vectors
  • structure and genetic organization of adenovirus vectors
  • adenovirus vectors
  • strategies to adapt adenoviral vectors for gene therapy applications - targeting and integration
  • adeno-associated viral vectors
  • gene-transfer tool - herpes simplex virus vectors
  • emerging viral vectors
  • advances in synthetic gene-delivery system techology
  • receptor-mediated gene delivery strategies
  • naked DNA gene transfer in mammalian cells
  • delivery systems and adjuvants for DNA vaccines
  • targets for gene therapy
  • the haemotopoietic system as a target for gene therapy
  • cancer immunotherapy
  • gene transfer and stem-cell transplantation
  • suicide genes - gene therapy applications using enzyme/prodrug strategies
  • the logic of anti-angiogenic gene therapy
  • apoptosis as a goal of cancer gene therapy
  • advances in gene therapy for HIV and other viral infections
  • progress toward gene therapy for nervous system diseases
  • targeted gene repair in mammalian cells using chimeric RNA/DNA oligonucleotides
  • human gene therapy - public policy and regulatory issues
  • ethical issues in human gene transfer research.

by "Nielsen BookData"

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Details

  • NCID
    BA3948833X
  • ISBN
    • 0879695285
  • LCCN
    98025205
  • Country Code
    us
  • Title Language Code
    eng
  • Text Language Code
    eng
  • Place of Publication
    Cold Spring Harbor, NY
  • Pages/Volumes
    xiii, 729 p.
  • Size
    23 cm
  • Classification
  • Subject Headings
  • Parent Bibliography ID
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