Fortschritte der Arzneimittelforschung Progress in drug research, or, Progrès des recherches pharmaoeutiques

著者

• Jucker, Ernest

書誌事項

Fortschritte der Arzneimittelforschung = Progress in drug research, or, Progrès des recherches pharmaoeutiques

hrsg. von Ernest Jucker

Birkhäuser, 1959-

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内容説明・目次

巻冊次

v. 14 ISBN 9783764305314

内容説明

Eleven years have elapsed since the appearance of the first Volume and it is with great pleasure that the Editor is now able to present Volume 14. During these eleven years various fields of drug research have undergone important, partly revolutionary, changes. A number of these have already been dealt with, so that the series PROGRESS IN DRUG RESEARCH contains a comprehensive review of a substantial part of our current knowledge. The Editor is particularly grateful for the opportunity of transmitting to those connected with the development of drugs the extensive knowledge of the Authors, who, without exception, are themselves actively engaged in research. Drug research is currently in a state of transformation: reconsideration in the light of the past and reorientation with a view to the future. To a large extent this is due to the tumultuous developments in the last 20 years, developments which are unparalleled in the history of medicine and the consequences of which cannot yet be completely evaluated. Unfortunately, however, the current situation is not devoid of its unpleasant and even tragic aspects, aspects which fall outside the research worker's sphere or influence. Those connected with drug research, be they in industry, in universities or in clinics, are aware of these problems, and, as a result of this awareness, are all the more in need of an aid which will assist them in ascertaining the current position and in fixing future goals.

目次

* Inhalt * Sommaire Vol. 14.- Reduction of Drug-Action by Drug Combination.- Drug-Macromolecular Interactions: Implications for Pharmacological Activity.- Interactions between Androgenic Anabolic Steroids and Glucocorticoids.- A new Approach to the Medical Interpretation of Shock.- Biological Activity in the Quinazolone Series.- Galenische Formgebung und Arzneimittel Wirkung. Neue Erkenntnisse und Feststellungen.- Synthetische und naturliche Acetylen-Verbindungen als Arzneistoffe.- Index Vol. 14.- Author and Paper Index - Autoren- und Artikelindex Index des auteurs et des articles, Vol. 1-14.

巻冊次

v. 15 ISBN 9783764305420

内容説明

Twelve years have elapsed since the appearance of the first volume and it is with great pleasure that the Editor is now able to present volume 15. During these twelve years various fields of drug research have undergone important, partly revolutionary, changes. A number of these have already been dealt with, so that the series PROGRESS IN DRUG RESEARCH contains a comprehensive review of a substantial part of our current knowledge. The Editor is particularly grateful for the opportunity of transmitting to those connected with the development of drugs the extensive knowledge of the Authors, who, without exception, are themselves actively engaged in research. Drug research is currently in a state of transformation: reconsideration in the light of the past and reorientation with a view to the future. To a large extent this is due to the tumultuous developments in the last 20 years, developments which are unparalleled in the history of medicine and the consequences of which cannot yet be completely evaluated. Unfortunately, however, the current situation is not devoid of its unpleasant and even tragic aspects, aspects which fall outside the research worker's sphere or influence. Those connected with drug research, be they in industry, in universities or in clinics, are aware of these problems, and, as a result of this awareness, are all the more in need of an aid which will assist them in ascertaining the current position and in fixing future goals.

目次

- Inhalt - Sommaire.- Ayurvedic Medicine - Past and Present.- The Psychotomimetic Agents.- Pharmacology of Clinically Useful Beta-Adrenergic Blocking Drugs.- On the Understanding of Drug Potency.- Stoffwechsel von Arzneimitteln als Ursache von Wirkungen, Nebenwirkungen und Toxizitat.- Basic Research in the US Pharmaceutical Industry.- Cyclopropane Compounds of Biological Interest.- Drug Action and Assay by Microbial Kinetics.- Index, Vol. 12-15.- Subject Index - Sachverzeichnis - Table des matieres, Vol. 1-15.- Author and Paper Index - Autoren- und Artikelindex - Index des auteurs et des articles, Vol. 1-15.

巻冊次

v. 16 ISBN 9783764306328

内容説明

Thirteen years have elapsed since the appearance of the first volume and it is with great pleasure that the Editor is now able to present volume 16. During these thirteen years various fields of drug research have undergone important, partly revolutionary, changes. A number of these have already been dealt with, so that the series PROGRESS IN DRUG RESEARCH contains a comprehensive review of a substantial part of our current knowledge. The Editor is particularly grateful for the opportunity of transmitting to those connected with the devel- opmentof drugs the extensive knowledge of the Authors, who, without exception, are themselves actively engaged in research. Drug research is currently in a state of transformation: reconsideration in the light of the past and reorientation with a view to the future. To a large extent this is due to the tumultuous developments in the last 20 years, developments which are unparalleled in the history of medicine and the consequences of which cannot yet be completely evaluated. Unfortunately, however, the current situation is not devoid of its unpleasant and even tragic aspects, aspects which fall outside the research worker's sphere or influence. Those connected with drug research, be they in industry, in universities or in clinics, are aware of these problems, and, as a result of this awareness, are all the more in need of an aid which will assist them in ascertaining the current position and in fixing future goals.

目次

- Inhalt - Sommaire.- Recent Developments in the Chemotherapy of Schistosomiasis.- Immunosuppression - Agents, Procedures, Speculations and Prognosis.- The Chemotherapy of Intestinal Nematodes.- The Art and Science of Contemporary Drug Development.- Pharmacology of the Brain: The Hippocampus, Learning and Seizures.- Biochemical Acyl Hydroxylations.- Lysostaphin: Model for a Specific Enzymatic Approach to Infectious Disease.- Cholinergic Mechanism-Monoamines Relation in Certain Brain Structures.- Tabellarische Zusammenstellung uber die Substruktur der Proteine.- Index, Vol. 16.- Subject Index - Sachverzeichnis - Table des matieres Vol. 1-16.- Author and Paper Index - Autoren- und Artikelindex - Index des auteurs et des articles, Vol. 1-16.

巻冊次

v. 17 ISBN 9783764306861

内容説明

Fourteen years have elapsed since the appearance of the first volume and it is with great pleasure that the Editor is now able to present volume 17. During these fourteen years various fields of drug research have undergone important, partly revolutionary, changes. A number of these have already been dealt with, so that the series PROGRESS IN DRUG RESEARCH contains a comprehensive review of a substantial part of our current knowledge. The Editor is particularly grateful for the opportunity of transmitting to those connected with the devel- opment of drugs the extensive knowledge of the Authors, who, without exception, are themselves actively engaged in research. Drug research is currently in a state of transformation: reconsideration in the light of the past and reorientation with a view to the future. To a large extent this is due to the tumultuous developments in the last 20 years, developments which are unparalleled in the history of medicine and the consequences of which cannot yet be completely evaluated. Unfortunately, however, the current situation is not devoid of its unpleasant and even tragic aspects, aspects which fall outside the research worker's sphere or influence.

目次

• - Inhalt - Sommaire vol. 17.- Enhancement and Inhibition of Microsomal Drug Metabolism.- Recent Advances in Electrophysiology of Antiarrhythmic Drugs.- The Red Blood Cell Membrane as a Model for Targets of Drug Action.- Human and Veterinary Anthelmintics (1965-71).- The Tetracyclines.- Progress in the Experimental Chemotherapy of Helminth Infections
• Part I, Trematode and Cestode Infections.- The Relationship of the Metabolism of Anticancer Agents to their Activity.- Prostaglandins.- The Oxidative Metabolism of Drugs and Other Foreign Compounds.- Index, Vol. 17.- Subject Index - Sachverzeichnis - Table des matieres, Vol. 12-17 ..- Author and Paper Index - Autoren- und Artikelindex - Index des auteurs et des articles, Vol. 1-17.

巻冊次

v. 18 ISBN 9783764307196

内容説明

The present 18th volume differs from previous volumes insofar as, with the exception of two contributions, it is exclusively concerned with problems of a single field, namely Tropical Medicine. This was occasioned by the Internatio- nal Symposium on the investigation and treatment of infectious tropical diseases held in Bombay in January 1974 and organized by the editor in collaboration with the Minister of Health of the State of Maharashtra, Dr. Rafiq Zakaria, the Director of the Hafl'kine Institute, Dr. B. Gaitonde, and with Dr. J. N. Banerjee, Dr. S. K. Bhattacharya and Mr. P. D'Souza. The Hafl'kine Institute celebrated on this occasion the 75th year of its existence and everyone entrusted with the organisation of the Symposium considered themselves fortunate to have been able to help in strengthening the contacts between Indian and foreign research workers, in the hope of, in this way, making a contribution to the fight against infectious tropical diseases. The editor hopes that the present 18th volume will represent comprehensive information on the topics treated at the Symposium; the 19th volume, which will soon appear, is concerned with the same area, so that the two volumes together should give a good picture of the many still unsolved problems. The editor would also like to take this opportunity of expressing his gratitude to his collaborator, Dr. A. Niif, who, as usual, performed valuable services in working over the manuscripts.

目次

* Inhalt * Sommaire * Vol. 18.- Introductory Remarks.- Haffkine - A Historical Appreciation.- Recent Progress in the Chemotherapy of Schistosomiasis.- Some Practical Problems of the Epidemiology of Leprosy in the Indian Context.- Teaching Tropical Medicine.- Implementation of Disease Control in Asia and Africa.- Some Neuropathologic and Cellular Aspects of Leprosy.- Surgical Amoebiasis.- Profiles of Tuberculosis in Rural Areas of Maharashtra.- New Perspectives on the Chemotherapy of Malaria, Filariasis and Leprosy.- Filariasis in India.- Recent Advances in the Treatment of Parasitic Infections in Man.- Toxoplasmosis.- Experimental Evaluation of Antituberculous Compounds, with Special Reference to the Effect of Combined Treatment.- Pathogenesis of Amebic Disease.- Preparing the Ground for Research: Importance of Data.- Problems of Malaria Eradication in India.- Functional Significance of the Various Components of the Influenza Virus.- Anti-Filariasis Campaign: Its History and Future Prospects.- Epidemiological and Biochemical Studies in Filariasis in Four Villages near Bombay.- Some often Neglected Factors in the Control and Prevention of Communicable Diseases.- The Leishmaniases.- Comparative Evaluation of Amoebicidal Drugs.- Toxicity of Propellants.- Recent Applications of Mass Spectrometry in Pharmaceutical Research.- Index, Vol. 18.- Subject Index * Sachverzeichnis * Table des matieres, Vol. 1-18.- Author and Paper Index * Autoren- und Artikelindex * Index des auteurs et des articles, Vol. 1-18.

巻冊次

v. 19 ISBN 9783764307578

内容説明

The 19th volume deals, as did its predecessor, with current problems of tropical medicine. Both volumes are based on various international Symposia which were held in Bombay on the occasion of the 75-year Platinum Jubilee of the Haffkine Institute in the Spring of 1974. The contributions in the 19th volume are based on lectures at thetast three Symposia which dealt with Helminthiasis, Diphtheria, Pertussis, Tetanus and Cholera. The 70 articles provide the reader with an impressive cross-section of the current state of specialized knowledge on the subject and the outstanding problems. Even today, researchers from various disciplines are still confronted with numerous unsolved problems in tropical medicine, and it is to be hoped that the 18th and 19th volumes will provide a stimulus for intensified research in the area of tropical medicine. The editor further hopes that, in the future, a still more fruitful co-operation between developed and developing countries will come about. The editor owes special thanks to Dr. Rafiq Zakaria, Minister, Dr. Gaitonde, as well as Dr. Anand and Dr. Chadha, who were responsible for the organisa- tion of the Symposia on which the 19th volume is based. Thanks are also extended to Dr. A. Niif for his conscientious revision of the manuscripts and correction of the galley proofs. In addition, thanks are due to the publishers and the printers, Birkhiiuser, especially to Dr. A. Birkhiiuser, Th. Birkhauser and C. Einsele for their accurate printing and fine presentation of the volume.

目次

• * Inhalt * Sommaire * Vol. 19.- 1 Helminthiasis.- Trial of a New Anthelmintic (Bitoscanate) in Ancylostomiasis in Children.- Bitoscanate in Children with Hookworm Disease.- Analysis of Symptoms and Signs Related with Intestinal Parasitosis in 5,215 Cases.- Experience with Bitoscanate in Hookworm Disease and Trichuriasis in Mexico.- Epidemiology and Public Health. Importance of Intestinal Nematode Infections in Latin America.- Effect of Hookworm Disease on the Structure and Function of Small Bowel.- Laboratory Methods in the Screening of Anthelmintics.- Clinical Field Trial of Bitoscanate in Necator americanus Infection, South Thailand.- A Comparative Study of Bitoscanate, Bephenium hydroxynaphthoate and Tetrachlorethylene in Hookworm Infection.- Reactivity of Bentonite Flocculation, Indirect Haemagglutination and Casoni Tests in Hydatid Disease.- A Field Trial with Bitoscanate in India.- Comparative Study of Bitoscanate, Bephenium hydroxynaphthoate and Tetrachlorethylene in Hookworm Disease.- Experience with Bitoscanate in Adults.- Clinical Experience with Bitoscanate.- Hookworm Anaemia and Intestinal Malabsorption Associated with Hookworm Infestation.- Immuno-Diagnosis of Helminthic Infections.- Immuno-Diagnosis in Filarial Infection.- Role of Periodic Deworming of Preschool Community in National Nutrition Programmes.- Mechanisms of Anthelmintic Action.- Chemotherapy of Intestinal Helminthiasis.- Comparative Efficacy of Newer Anthelmintics.- 2 Diphtheria, Pertussis and Tetanus.- Pertussis Agglutinins and Complement Fixing Antibodies in Whooping Cough.- Tetanus Neonatorum.- Tetanus in Children.- Problems in Preparation, Testing and Use of Diphtheria, Pertussis and Tetanus Vaccines.- Studies on Diphtheria in Bombay.- Autonomic Dysfunction as a Problem in the Treatment of Tetanus.- Immunization of a Village, a New Approach to Herd Immunity.- Epidemiology of Pertussis.- Host Factors in the Response to Immunization.- Progress in Immunization (Popular Lecture).- Iron and Diphtheria Toxin Production.- Tetanus in Punjab with Particular Reference to the Role of Muscle Relaxants in Its Management.- Present Data on the Pathogenesis of Tetanus.- Tetanus: General and Pathophysiological Aspects
• Achievements, Failures, Perspectives of Elaboration of the Problem.- Therapeutic Measurement in Tetanus.- Cholinesterase Restoring Therapy in Tetanus.- Epidemiology of Diphtheria.- What Makes a Good Pertussis Vaccine?.- Vaccine Composition in Relation to Antigenic Variation of the Microbe: Is Pertussis Unique? (Guest Lecture).- Clinical Study of Diphtheria, Pertussis and Tetanus.- Role of Beta-Adrenergic Blocking Drug Propranolol in Severe Tetanus.- Tetanus: Situational Clinical Trials and Therapeutics.- Growth of Clostridium tetani in vivo.- Tetanus and Its Prevention.- Gram-Negative Bacterial Endotoxin and the Pathogenesis of Fever.- Age Profile of Diphtheria in Bombay.- Diphtheria.- Mode of Death in Tetanus.- Cephalic Tetanus.- The Problem of Diphtheria as Seen in Bombay.- 3 Cholera.- Recent Studies on Genetic Recombination in Vibrio cholerae.- Interbiotype Conversion of Cholera Vibrios by Action of Mutagens.- The Antibody Basis of Local Immunity to Experimental Cholera Infection in the Rabbit Ileal Loop.- Contribution of Haffkine to the Concept and Practice of Controlled Field Trials of Vaccines.- Studies on V. parahaemolyticus Infection in Calcutta as Compared to Cholera Infection.- Impact of Researches in India on the Control and Treatment of Cholera.- Bacteriology at the Periphery of the Cholera Pandemic.- Effect of Drugs on Cholera Toxin Induced Fluid in Adult Rabbit Ileal Loop.- The Management of Acute Diarrhea in Children: an Overview.- Relationship of Induced Antibody Titres to Resistance to Experimental Human Infection.- Virulence-Enhancing Effect of Ferric Ammonium Citrate on Vibriocholerae.- Antibody Response to two Cholera Vaccines in Volunteers.- Recent Advances in Cholera Pathophysiology and Therapeutics.- An Extensive Community Outbreak of Acute Diarrhoeal Diseases in Children.- Epidemiology of Cholera in Hyderbad.- Studies on Vibrio parahaemolyticus in Bombay.- Epidemiological Studies on Cholera in Non-Endemic Regions with Special Reference to the Problem of Carrier State During Epidemic and Non-Epidemic Period.- The Current Status of Cholera Toxoid Research in the United States.- Cell-Wall Antigens of V. cholerae and Their Implication in Cholera Immunity.- Index, Vol. 19.- Subject Index * Sachverzeichnis * Table des matieres, Vol. 1-19.- Author and Paper Index * Autoren- und Artikelindex * Index des auteurs et des articles, Vol. 1-19.

巻冊次

v. 20 ISBN 9783764308315

内容説明

Volumes 18 and 19 of "Progress in Drug Research" differed from the earlier volumes insofar as they were concerned almost exclusively with problems in the field of Tropical Medicine. The editor and publishers believed that in this way some contribution could be made to the solution of some of the many problems with which the developing countries are burdened. The 20th volume, however, is in the customary form; it contains 17 contributions from various areas of drug research and therapy. Whereas the articles concentrate on a short representation of the progress which has already been made, nevertheless reference is also made to the many unsolved problems within the particular areas. The editor hopes that the 20th volume will not only represent a comprehensive review but will also be of some use in focusing further investigations on problems of medicine that have still not been overcome. The editor would also like to take this opportunity of expressing his gratitude to Dr. A. Naffor carefully working over the manuscripts and correcting proofs. Thanks are also due to the publishers and the printers, Druckerei Birkhauser, especially Dr. A. Birkhauser, Th. Birkhauser and C. Einsele, for their painstaking work on the printing and lay-out of the volume. August 1976 Dr. E. JUCKER Sandoz AG, Basel Vorwort Die Bande 18 und 19 der "Fortschritte der Arzneimitte1forschung" wichen insofern von den vorhergehenden Banden ab, a1s sie fast ausschliess1ich Prob1eme der Tropenkninkheiten behandelten.

目次

The State of Medicinal Science.- Adrenergic Beta-Blocking Agents.- Recent Progress in Research on Narcotic Antagonists.- Stereoselectivity and Affinity in Molecular Pharmacology.- Industrial Research in the Quest for New Medicines.- Changing Influences on Goals and Incentives in Drug Research and Development.- The Interface between Drug Research, Marketing, Management, and Social, Political and Regulatory Forces.- Antihypertensive Agents.- Transport and Accumulation in Biological Cell Systems Interacting with Drugs.- Isolation and Characterization of Membrane Drug Receptors.- The Levamisole Story.- Fundamental Structures in Drug Research.- Protozoan and Helminth Parasites - A Review of Current Treatment.- The Current Status of Cancer Chemotherapy.- Problems of Medical Practice and of Medical-Pharmaceutical Research.- Cell-Kinetic and Pharmacokinetic Aspects in the Use and Further Development of Cancerostatic Drugs.- Where Is Immunology Taking Us?.- Index, Vol. 20.- Subject Index * Sachverzeichnis * Table des matieres, Vol. 1-20.- Author and Paper Index * Autoren- und Artikelindex * Index des auteurs et des articles, Vol. 1-20.

巻冊次

v. 21 ISBN 9783764309190

内容説明

Volume 21 of "Progress in Drug Research" contains 5 contributions from various areas of drug research and therapy. As in previous volumes, in the present volume the authors have also tried not only to summarise the current status of particular fields of drug research, but also to provide leads for future research activity. The various contributions in this volume will be of especial value not only to those actively concerned in resolving the diverse problems in drug research, but also to those who wish to keep abreast ofthe latest developments in- fluencing modem therapy. In addition, it is believed that volume 21 and the previous 20 volumes of "Progress in Drug Research" so far published represent a useful reference work of an encyclopaedic character. The editor would also like to take this opportunity of expressing his gratitude to Dr. A. Naffor carefully working over the manuscripts and correcting proofs. Thanks are also due to the publishers and the printers, Druckerei Birkhauser, especially to Dr. A. Birkhauser, Th. Birkhiiuser and C. Einsele, for their painstaking work on the printing and lay-out of the volume. August 1977 Dr. E. JUCKER Sandoz AG, Basel Vorwort Der 21. Band der "F ortschritte der Arzneimittelforschung" umfasst 5 Beitriige aus verschiedenen Gebieten der Arzneimittelforschung> und der Therapie.

目次

Development of Antibacterial Agents of the Nalidixic Acid Type.- The Pharmacokinetic Bases of Biological Response Quantification in Toxicology, Pharmacology and Pharmacodynamics.- Methods of Monitoring Adverse Reactions to Drugs.- Contraception - Retrospect and Prospect.- Agents Acting on Central Dopamine Receptors.- Index Vol. 21.- Subject Index * Sachverzeichnis * Table des matieres, Vol. 1-21.- Author and Paper Index * Autoren- und Artikelindex * Index des auteurs et des articles, Vol. 1-21.

巻冊次

v. 22 ISBN 9783764310004

内容説明

Volume 22 of 'Progress in Drug Research' contains 8 contributions from vari- ous areas of drug research and therapy. As in previous volumes, in the present volume the authors have also tried not only to summarize the current status of particular fields of drug research, but also to provide leads for future research activity. The various contributions in this volume will be of especial value not only to those actively concerned in resolving the diverse problems in drug research, but also to those who wish to keep abreast of the latest developments influencing modem therapy. In addition, it is believed that volume 22 and the previous 21 volumes of 'Progress in Drug Research' so far published represent a useful reference work of an encyclopaedic character. The editor would also like to take this opportunity of expressing his gratitude to those who reviewed the previous volumes of this series of monographs and, by doing so gave useful advice for the future volumes. At the same time, thanks are expressed to Dr. A. Naf for carefully working over the manuscripts and correcting proofs. Thanks are also due to the publishers and the printers, Druckerei Birkhauser, especially to Messrs. Th. Birkhauser and C. Einsele. Unfortunately, this is the last volume which went into ptess during Dr. A. Birkhauser's lifetime; he passed away on March 4, 1978 and the editor would like to stress the fact'tl;tat.

目次

Contents*Inhalt*Sommaire*Vol. 22.- Aspects of social pharmacology.- Fundamental structures in drug research II.- Antifungal agents.- Analgesics and their antagonists: Recent developments.- The benzodiazepine story.- Antiviral agents.- Klinisch-pharmakologische Kriterien in der Bewertung eines neuen Antibiotikums. Grundlagen und methodische Gesichtspunkte.- Drug research and human sleep.- Index Vol. 22.- Subject Index*Sachverzeichnis*Table des matieres, Vol. 1-22.- Author and Paper Index*Autoren- und Artikelindex*Index des auteurs et des articles, Vol. 1-22.

巻冊次

v. 23 ISBN 9783764310707

内容説明

Volume 23 includes six contributions as well as the Index for volumes 16-23. The key-word Index, like those of volumes II and IS, provides the reader with a simple cross-reference to all fields of possible interest, making this series of monographs even more useful as an encyclopaedic reference work. The scientific articles treat various topical areas of drug research, reviewing developments and indicating unsolved problems. The editor hopes to have provided the reader with a useful orientation and reference work. Experience over the last few years has shown that a more rapid publica- tion of the individual volumes better meets the wishes of readers by keeping pace with the speed of modem research. The present volume, as well as its predecessor, has broken the tradition of 500-600-page volumes in the hope of better satisfying the needs of the readers of this series. Finally, thanks are due to all those who have provided helpful criticism of past volumes, thereby providing valuable advice regarding the form of future volumes, and to Dr. A. Niif for his careful revision of the manu- scripts and correction of the proofs. Thanks are also due to the publish- ers and printers Birkhiiuser, in particular Messrs. Th. Birkhiiuser and C. Einsele. July 1979 Dr. E. Jucker Sandoz Ltd., Basel Vorwort Der 23. Band umfasst sechs Beitrage nebst dem Index der Bande 16-23.

目次

/ Inhalt / Sommaire.- Some unsolved problems with vaccines.- Adverse reactions of sugar polymers in animals and man.- The impact of natural product research on drug discovery.- On the relation between chemical structure and function in certain tumor promoters and antitumor agents.- Lipophilicity and drug activity.- Quantitative structure-activity relationships.- Index Vol. 16-23.- Subject Index * Sachverzeichnis * Table des matieres, Vol. 1-23.- Author and Paper Index * Autoren- und Artikelindex * Index des auteurs et des articles, Vol. 1-23.

巻冊次

v. 24 ISBN 9783764311483

内容説明

Volume 24 includes six contributions, the author and paper index of volumes 1-24 and the key-word index. Since volume 23 included an index for volumes 16-23 the reader has the possibility to use these monographs as an encyclopedia and is in the position to find references to almost all fields of drug research. The editor hopes that the articles of the present volume will prove interesting and useful to many scientists and would be grateful to receive suggestions and opinions from readers, as in the past case over the 20 years in which this series of monographs has existed. In this respect, thanks are due to all colleagues who have provided helpful criticism of past volumes, thereby helping the editor in his work. Dr. A. Naf again has assisted the editor and has carefully reviewed all manuscripts, formulae and references, and has corrected the proofs. Thanks are due to him for this immense work. At the same time, the editor would like to thank the publishers and printers, Verlag Birkhliu- ser, in particular Messrs. Th. Birkhliuser and C. Einsele, for the excellent cooperation and the work they have accomplished.

目次

* Inhalt * Sommaire.- Noise analysis and channels at the postsynaptic membrane of skeletal muscle.- Relationships between structure and function of convulsant drugs.- The experimental biologist and the medical scientist in the pharmaceutical industry.- Recent developments in disease-modifying antirheumatic drugs.- Chemotherapy of cestode infections.- Quaternary ammonium salts - advances in chemistry and pharmacology since 1960.- Index vol. 24.- Subject Index* Sachverzeichnis * Table des matieres, vol. 1-24.- Author and Paper Index* Autoren- und Artikelindex* Index des auteurs et des articles, vol. 1-24.

巻冊次

v. 26 ISBN 9783764312619

内容説明

Volume 26 of 'Progress in Drug Research' contains 10 articles, a subject index for this volume, an alphabetic subject index for volumes 1-26, and an author and subject index for all the volumes which have so far been published. The contributions of volume 26 cover a wide field of drug research and therapy, and some are directed towards tropical deseases. As in previous volumes, the authors have also tried not only to summa- rise the current status of particular fields of drug research, but also to provide leads for future research activity. The articles in this volume will be of special value not only to those actively engaged in resolving the diverse problems in drug research, but also to those who wish to keep abrest of the latest developments influencing modern therapy. In addition, it is believed that the 26 volumes of "Progress in Drug Research" now available represent a useful reference work of an encyclo- paedic character.

目次

* Inhalt * Sommaire.- Chemotherapy of hookworm infections.- Drug and its action according to Ayurveda.- Mechanism of drugs action on ion and water transport in renal tubular cells.- Metabolic activation of chemical carcinogens.- Antibiotics in the chemotherapy of malaria.- Drugs affecting the renin-angiotensin system.- A review of the continuum of drug-induced states of excitation and depression.- Search of pharmaceutically interesting quinazoline derivatives: Efforts and results (1969-1980).- Some reflections on the chemotherapy of tropical diseases: past, present and future.- Central control of arterial pressure by drugs.- Index * Sachverzeichnis * Table des matieres, Vol.26.- Subject Index * Sachverzeichnis * Table des matieres, Vol. 1-26.- Author and Paper Index * Autoren- und Artikelindex * Index des auteurs et des articles, Vol. 1-26.

巻冊次

v. 27 ISBN 9783764313654

内容説明

Volume 27 of "Progress in Drug Research" contains 5 articles, a subject index for this volume, an alphabetic subject 4ldex for volumes 1-27, and an author and subject index for altthe volumes which have so far been published. The contributions of volume 27 are particularly concerned with fungal disease, with benzimidazole anthelmintics and with the chemistry and pharmacology of quinuclidines, azoles, and nitroimida- zoles. The authors have tried, not only to summarize the current status of particular fields of drug research, but also to provide leads for future research activity. The articles of this volume will be of special value to those actively engaged in drug research, and to those who wish to keep abrest of the latest developments influencing modem therapy. In addi- tion, it is believed that the 27 volumes of "Progress in Drug Research" now available represent a useful reference work of encyclopedic charac- ter. The editor would like to take the occasion of the publication of this volume to express his gratitude both to the authors and to the readers. The authors have willingly1undertaken'the great labor of writing signifi- cant topical contributions, hnd many readers have helped the editor with criticism and advise. With these thanks, the editor would like also to express his gratitude to the publisher, Birkhauser Verlag Basel, particu- larly to Messrs. Th. Birkhauser and C. Einsele, and their associates for the excellent cooperation.

目次

* Inhalt * Sommaire.- Further developments in research on the chemistry and pharmacology of synthetic quinuclidine derivatives.- Ketoconazole, a new step in the management of fungal disease.- The benzimidazole anthelmintics - chemistry and biological activity.- Nitroimidazoles as chemotherapeutic agents.- Fifteen years of structural modifications in the field of antifungal monocyclic 1-substituted 1H-azoles.- Index * Sachverzeichnis * Table des matieres, Vol.27.- Subject Index * Sachverzeichnis * Table des matieres, Vol. 1-27.- Author and Paper Index * Autoren- und Artikelindex * Index des auteurs et des articles, Vol. 1-27.

巻冊次

v. 28 ISBN 9783764315566

内容説明

Volume 28 of 'Progress in Drug Research' contains 8 articles, a subject index for this volume, an alphabetic subject index for volumes 1-28, and an author and subject index for all the volumes which have so far been published. The contributions of volume 28 are particularly con- cerned with biogenic amines, with immunology and the pharmacology of the immune system, with antiviral agents, with amino-quinoline an- timalarials, with the axoplasmic transport, with drug treatment of asthma and with the role of adipose tissue in the distribution and stor- age of drugs. The authors have tried, and I think they have succeded, not only to summarize the current status of particular fields of drug research, but also to provide leads for future research activity. The articles of this volume will be of special value to those actively engaged in drug re- search, and to those who wish to keep abrest ofthe latest developments influencing modern therapy. In addition, it is believed that the 28 volu- mes of 'Progress in Drug Research' now available represent a useful reference work of encyclopedic character. l The editor would like to take the bccasion of the publication of this volume to express his gratitude both to ,the authors and to the readers.

目次

Contents*Inhalt*Sommaire.- Biogenic amines and drug research.- Pharmacology and toxicology of axoplasmic transport.- The pharmacology of the immune system.- Drug treatment of asthma.- Antiviral agents 1978-1983.- Recent developments in 8-amino-quinoline antimalarials.- Immunology in drug research.- The role of adipose tissue in the distribution and storage of drugs.- Index*Sachverzeichnis*Table des matieres, Vol. 28.- Subject*Index*Sachverzeichnis*Table des matieres, Vol. 1-28.- Author and Paper Index*Autoren- und Artikelindex*Index des auteurs et des articles, Vol. 1-28.

巻冊次

v. 29 ISBN 9783764316723

内容説明

Volume 29 of 'Progress in Drug Research' contains 10 articles, a sub- ject index for this volume, an alphabetic index of articles for volumes 1-29, and an author und subject index for all the volumes which have so far been published. The contributions of volume 29 are particularly concerned with drugs in general, hypertension and cardiovascular drugs, atherosclerosis, teratogenic hazards and carcinogenecity, hist- amine, dopamine agonists, tetrahydroquinolines and /J-carbolines, and meddicinal research. The authors have tried, and I think they have succeded, not only to summarize the current status of particular fields of drug research, but also to provide leads for future research activity. The articles of this vo- lume will be of special value to those actively engaged in drug re- search, and to those who wish to keep abrest of the latest developments influencing modern therapy. In addition, it is believed that the 29 vo- lumes of 'Progress in Drug Research' now available represent a useful reference book of encyclopedic character. The editor would like to take the occasion of the publication of this volume to express his grati- tude both to the authors and to the readers. The authors have willingly . undertaken the great labor of writing significant topical contributions, and many readers have helped the editor with criticism and advise. With these thanks, the editor would like to express his gratitude to the publishers, Birkhauser Verlag Basel, particularly to Messrs. H. 1. Ben- der, C. Einsele and A.

目次

Update of cardiovascular drug interactions.- Platelets and Atherosclerosis.- Structures, properties and disposition of drugs.- Medicinal Research: Retrospectives and perspectives.- A review of advances in prescreening for teratogenic hazards.- Carcinogenicity testing of drugs.- Recent advances in drugs against hypertension.- Drug inhibition of mast secretion.- Dopamine agonists: structure-activity relationships.- Tetrahydroisoquinolines and ?-carbolines: putative natural substances in plants and mammals.- Index * Sachverzeichnis * Table des matieres, Vol. 29.- Index of Titles * Verzeichnis der Titel * Index des titres, Vol. 1-29.- Author and Paper Index * Autoren- und Artikelindex * Index des auteurs et des articles, Vol. 1-29.

「Nielsen BookData」 より

• NII書誌ID(NCID): BA39512445
• ISBN:
  • 3764305312
  • 3764305428
  • 3764306327
  • 3764306866
  • 3764307196
  • 3764307579
  • 3764308311
  • 3764309199
  • 3764310006
  • 3764310707
  • 3764311487
  • 3764311797
  • 3764312610
  • 376431365X
  • 3764315563
  • 3764316721
• 出版国コード: sz
• タイトル言語コード: ger
• 本文言語コード: ger
• 出版地: Basel
• ページ数/冊数: v.
• 大きさ: 25 cm