Bisphosphonates in clinical oncology : the development on pamidronate

Bibliographic Information

Bisphosphonates in clinical oncology : the development on pamidronate

B. Thürlimann (ed.)

(Recent results in cancer research, 149)

Springer, 1999

Other Title

Bisphosphonates in clinical oncology : focus on pamidronate

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

This book provides a clinically oriented overview on the patho-physiological background and the use of bisphosphonates in oncology. The clinical development of pamidronate to treat tumor-induced hypercalcemia and malignant osteolytic bone disease is demonstrated, as well as the results of pivotal studies. New important findings on how to best use pamidronate in certain indications are given and put in perspective. The author discusses patient management guidelines as well as pharmaco-economic aspects important for the readers.

Table of Contents

Physiology and Pathophysiology of Bone.- Factors Regulating Calcium Hmomeostasis and Bone Resorption/Bone Formation.- Pharmacological Treatment of Bone Disorders.- Pamidronate.- Recent Developments and Future Directions.-

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