DNA and aspects of molecular biology

Author(s)

    • Kool, Eric T.

Bibliographic Information

DNA and aspects of molecular biology

volume editor, Eric T. Kool

(Comprehensive natural products chemistry / editors-in-chief, Sir Derek Barton, Koji Nakanishi ; executive editor, Otto Meth-Cohn, v. 7)

Elsevier, 1999

Available at  / 54 libraries

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Note

Includes index

Description and Table of Contents

Description

Hardbound. This volume is intended to cover the chemistry of one of the most widely studied and important natural products, DNA. Discussed in detail are physicochemical properties of the molecule itself as well as small-molecule natural products that are known to interact with it. Also included are methods to synthesize and manipulate DNA and modified analogues. Twenty chapters are devoted to this overall topic.The first five relate to the structure of DNA; the first focuses on thermodynamics and kinetics of double helix formation; the next two describe triple- and tetra- helical structures formed by DNA; and the last two focus on methods for probing DNA structure (specifically, NMR methods and chemical probing methods, respectively).Chapters 6-12 focus on the chemistry of natural DNA and modified analogues. The first of these addresses nonenzymatic methods for synthesizing DNA, and the next chapter, on methods for attachment of reporter groups t

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Details

  • NCID
    BA4018783X
  • ISBN
    • 0080431593
  • Country Code
    ne
  • Title Language Code
    eng
  • Text Language Code
    eng
  • Place of Publication
    Amsterdam ; Tokyo
  • Pages/Volumes
    xxxviii, 733 p.
  • Size
    28 cm
  • Classification
  • Subject Headings
  • Parent Bibliography ID
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