Cell behaviour : control and mechanism of motility
著者
書誌事項
Cell behaviour : control and mechanism of motility
（Biochemical Society symposium, no. 65）
Portland Press, c1999
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注記
At head of title: 4th Abercrombie Conference on Cell Behaviour held at St Catherine's College, Oxford, 28 September-1 October 1997
Includes bibliographies and index
内容説明・目次
内容説明
This volume describes molecular and genetic advances in the study of one of the most fundamental and yet least understood processes of life: the movement of cells. Cell locomotion lies at the basis of embryological development, wound healing and the spread of cancers. The recent advances in identifying the molecular components of cell motility can be found in many publications but this text provides a synthesis of the molecular and phenomenological aspects that will be required for an understanding of the controlling processes that underlie cell behaviour. The book should benefit final year students studying molecular/cell biology but it is primarily aimed at postgraduate research workers in all biomolecular sciences who need to understand the wider implications of their research. Besides cell and molecular biologists, these will include workers in oncology, vascular biology, tissue repair and cell engineering.
目次
- Part 1 Introduction: patterns of cellular activities based on protein sorting in cell motility, endocytosis and cytokinesis. Part 2 Motile responses: new depths in cell behaviour - reactions of cells to nanotopography
- self-organization of tissue-equivalents - the nature and role of contact guidance
- extracellular regulation of cancer invasion - the E-cadherin/cantenin and other pathways. Part 3 Signal transduction: towards a structure model of an integrin
- integrin-mediated cell adhesion - the cytoskeletal connection
- Wnt factors in axonal remodelling and synaptogenesis
- Rho family proteins and cell migration
- Rho-like GTPases - their role in cell adhesion and invasion. Part 4 Cytoskeletal dynamics: microtubule involvement in regulating cell contractility and adhesion-dependent signalling - a possible mechanism for polarization of cell motility
- organization and polarity of actin filament networks in cells - implications for the mechanism of myosin-based cell motility
- network contraction model for cell translocation and retrograde flow
- centrosomes, microtubules and cell migration
- cell migration as a five-step cycle. Part 5 Dynamics of motility: cytoskeletal protein mutations and cell motility in "Dictyostelium"
- cell crawling two decades after Abercrombie
- using molecular genetics as a tool in understanding crawling cell locomotion in myoblasts
- forces in cell locomotion. Part 6 Prospects: a dozen questions about how tissue cells crawl.
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